Western Blot (WB)
(Western Blot detection against Immunogen (50.97kD).)
Mouse anti-Human PILRA Monoclonal Antibody | anti-PILRA antibody
PILRA (Paired immunoglobulin-like Type 2 Receptor alpha, Cell Surface Receptor FDF03, Inhibitory Receptor PILR-alpha, FDF03) (Biotin)
Gene Names
PILRA; FDF03
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PILRA; Monoclonal Antibody; PILRA (Paired immunoglobulin-like Type 2 Receptor alpha; Cell Surface Receptor FDF03; Inhibitory Receptor PILR-alpha; FDF03) (Biotin); anti-PILRA antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
3C2
Specificity
Recognizes human PILRA.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-PILRA antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full-length recombinant corresponding to aa1-227 from human PILRA (AAH17812) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MGRPLLLPLLPLLLPPAFLQPSGSTGSGPSYLYGVTQPKHLSASMGGSVEIPFSFYYPWELATAPDVRISWRRGHFHGQSFYSTRPPSIHKDYVNRLFLNWTEGQKSGFLRISNLQKQDQSVYFCRVELDTRSSGRQQWQSIEGTKLSITQGQQRTKATTPAREPFQNTEEPYENIRNEGQNTDPKLNPKLHLTQSTSQPPSPQEPPERDPVLCLKGLTNGQPSQD
Conjugate
Biotin
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot detection against Immunogen (50.97kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (50.97kD).)
Western Blot (WB)
(PILRA monoclonal antibody, Western Blot analysis of PILRA expression in Hela NE.)
Western Blot (WB)
(PILRA monoclonal antibody, Western Blot analysis of PILRA expression in Hela NE.)
Testing Data
(Detection limit for recombinant GST tagged PILRA is ~3ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged PILRA is ~3ng/ml as a capture antibody.)
Related Product Information for anti-PILRA antibody
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described. [provided by RefSeq]
Product Categories/Family for anti-PILRA antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
19,898 Da
NCBI Official Full Name
Homo sapiens paired immunoglobin-like type 2 receptor alpha, mRNA
NCBI Official Synonym Full Names
paired immunoglobin like type 2 receptor alpha
NCBI Official Symbol
PILRA
NCBI Official Synonym Symbols
FDF03
NCBI Protein Information
paired immunoglobulin-like type 2 receptor alpha
Protein Family
NCBI Description
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described. [provided by RefSeq, Jul 2008]
Research Articles on PILRA
Similar Products
Product Notes
The PILRA (Catalog #AAA6143567) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PILRA (Paired immunoglobulin-like Type 2 Receptor alpha, Cell Surface Receptor FDF03, Inhibitory Receptor PILR-alpha, FDF03) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PILRA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PILRA for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PILRA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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