Western Blot (WB)
(Western Blot analysis of MCF-7 cells using PGRMC1 Monoclonal Antibody at dilution of 1:2000)
Mouse PGRMC1 Monoclonal Antibody | anti-PGRMC1 antibody
PGRMC1 Monoclonal Antibody
Gene Names
PGRMC1; IZA; MPR; Dap1; HPR6.6
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Protein G purification
Synonyms
PGRMC1; Monoclonal Antibody; PGRMC1 Monoclonal Antibody; HPR6.6; Membrane associated progesterone receptor component 1; Membrane-associated progesterone receptor component 1; mPR; PGRC1; PGRMC; Pgrmc1; Progesterone binding protein; Progesterone receptor membrane component 1; anti-PGRMC1 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1C10D11
Purity/Purification
Protein G purification
Concentration
1mg/mL (varies by lot)
Sequence Length
143
Applicable Applications for anti-PGRMC1 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:1000-1:10000
IHC: 1:50-1:500
IHC: 1:50-1:500
Immunogen
Fusion protein of PGRMC1
Buffer
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Western Blot (WB)
(Western Blot analysis of MCF-7 cells using PGRMC1 Monoclonal Antibody at dilution of 1:2000)
Western Blot (WB)
(Western Blot analysis of MCF-7 cells using PGRMC1 Monoclonal Antibody at dilution of 1:2000)
Related Product Information for anti-PGRMC1 antibody
Progesterone receptor membrane component 1 (PGRMC1) is a member of a multi-protein progesterone-binding complex. However, PGRMC1 shares homology with cytochrome b5-related proteins rather than hormone receptors. It is a heme binding protein with biding sites for Src homology (SH2) and SH3 domain-containing proteins. PGRMC1 is overexpressed in a variety of cancers, and thus represents an important biomarker for cancer progression and a potential target for anticancer drugs. In nonmalignant tissues, PGRMC1 is highly expressed in the liver and kidney.
Product Categories/Family for anti-PGRMC1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated: 22kDa
Observed: 25kDa
Observed: 25kDa
NCBI Official Full Name
membrane-associated progesterone receptor component 1 isoform 2
NCBI Official Synonym Full Names
progesterone receptor membrane component 1
NCBI Official Symbol
PGRMC1
NCBI Official Synonym Symbols
IZA; MPR; Dap1; HPR6.6
NCBI Protein Information
membrane-associated progesterone receptor component 1
UniProt Protein Name
Membrane-associated progesterone receptor component 1
Protein Family
UniProt Gene Name
PGRMC1
UniProt Synonym Gene Names
mPR
NCBI Description
This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney. [provided by RefSeq, Mar 2010]
Uniprot Description
Component of a progesterone-binding protein complex (PubMed:28396637). Binds progesterone (PubMed:25675345). Has many reported cellular functions (heme homeostasis, interaction with CYPs).
Research Articles on PGRMC1
Similar Products
Product Notes
The PGRMC1 pgrmc1 (Catalog #AAA2527508) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PGRMC1 Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PGRMC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:1000-1:10000 IHC: 1:50-1:500. Researchers should empirically determine the suitability of the PGRMC1 pgrmc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGRMC1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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