Western Blot (WB)
(Western blot detection of p60 katanin in K562,Hela cell lysates using p60 katanin Rabbit mAb(1:1000 diluted). Predicted band size:56kDa. Observed band size:56kDa.)
Rabbit anti-Human p60 katanin Monoclonal Antibody | anti-KATNA1 antibody
p60 katanin Rabbit mAb
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Immunofluorescence
Purity
Affinity purified
Synonyms
p60 katanin; Monoclonal Antibody; p60 katanin Rabbit mAb; Katanin p60 ATPase-containing subunit A1; anti-KATNA1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
R05-3B9
Purity/Purification
Affinity purified
Form/Format
Supplied in 50nM Tris-Glycine (pH7.4), 0.15M Nacl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Applicable Applications for anti-KATNA1 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes
WB: 1:1000-1:5000
ICC/IF: 1:20
ICC/IF: 1:20
Immunogen
A synthetic peptide of human p60 katanin
Conjugation
Unconjugated
Modification
Unmodification
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze/thaw cycle.
Western Blot (WB)
(Western blot detection of p60 katanin in K562,Hela cell lysates using p60 katanin Rabbit mAb(1:1000 diluted). Predicted band size:56kDa. Observed band size:56kDa.)
Western Blot (WB)
(Western blot detection of p60 katanin in K562,Hela cell lysates using p60 katanin Rabbit mAb(1:1000 diluted). Predicted band size:56kDa. Observed band size:56kDa.)
Related Product Information for anti-KATNA1 antibody
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60kDa ATPase (p60 subunit A 1) and an 80kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Feb 2011]
Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35,319 Da
NCBI Official Full Name
katanin p60 ATPase-containing subunit A1 isoform 2
NCBI Official Synonym Full Names
katanin p60 (ATPase containing) subunit A 1
NCBI Official Symbol
KATNA1
NCBI Protein Information
katanin p60 ATPase-containing subunit A1; KATNA1; katanin p60 (ATPase-containing) subunit A 1; katanin p60 subunit A1; p60 katanin
UniProt Protein Name
Katanin p60 ATPase-containing subunit A1
UniProt Gene Name
KATNA1
UniProt Entry Name
KTNA1_HUMAN
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Product Notes
The KATNA1 katna1 (Catalog #AAA4752933) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The p60 katanin Rabbit mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's p60 katanin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF). WB: 1:1000-1:5000 ICC/IF: 1:20. Researchers should empirically determine the suitability of the KATNA1 katna1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p60 katanin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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