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Testing Data (Detection limit for recombinant GST tagged P2RX2 is 1 ng/ml as a capture antibody.)

Mouse P2RX2 Monoclonal Antibody | anti-P2RX2 antibody

P2RX2 (Purinergic Receptor P2X, Ligand-gated Ion Channel, 2, MGC129601, P2X2) (AP)

Gene Names
P2RX2; P2X2; DFNA41
Applications
Western Blot
Purity
Purified
Synonyms
P2RX2; Monoclonal Antibody; P2RX2 (Purinergic Receptor P2X; Ligand-gated Ion Channel; 2; MGC129601; P2X2) (AP); Purinergic Receptor P2X; P2X2; anti-P2RX2 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
3D5
Specificity
Recognizes P2RX2.
Purity/Purification
Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Sequence Length
399
Applicable Applications for anti-P2RX2 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
P2RX2 (NP_036358.2, 128aa-205aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
KNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPAS
Conjugate
AP
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Testing Data

(Detection limit for recombinant GST tagged P2RX2 is 1 ng/ml as a capture antibody.)

Testing Data (Detection limit for recombinant GST tagged P2RX2 is 1 ng/ml as a capture antibody.)

Western Blot (WB)

(P2RX2 monoclonal antibody (M02), clone 3D5. Western Blot analysis of P2RX2 expression in MCF-7.)

Western Blot (WB) (P2RX2 monoclonal antibody (M02), clone 3D5. Western Blot analysis of P2RX2 expression in MCF-7.)
Related Product Information for anti-P2RX2 antibody
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene. [provided by RefSeq]
Product Categories/Family for anti-P2RX2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
P2X purinoceptor 2 isoform I
NCBI Official Synonym Full Names
purinergic receptor P2X 2
NCBI Official Symbol
P2RX2
NCBI Official Synonym Symbols
P2X2; DFNA41
NCBI Protein Information
P2X purinoceptor 2
UniProt Protein Name
P2X purinoceptor 2
Protein Family
UniProt Gene Name
P2RX2
UniProt Synonym Gene Names
P2X2; P2X2
UniProt Entry Name
P2RX2_HUMAN

NCBI Description

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2013]

Uniprot Description

P2X2: Binding of this ligand-gated ion channel to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Belongs to the P2X receptor family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Channel, cation; Channel, ligand-gated; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 12q24.33

Cellular Component: apical plasma membrane; integral to nuclear inner membrane; integral to plasma membrane; plasma membrane; receptor complex

Molecular Function: ATP binding; ATP-gated cation channel activity; identical protein binding; ligand-gated ion channel activity; purinergic nucleotide receptor activity

Biological Process: behavioral response to pain; blood coagulation; detection of hypoxic conditions in blood by carotid body chemoreceptors; neuromuscular junction development; neuromuscular synaptic transmission; peristalsis; positive regulation of calcium-mediated signaling; protein homooligomerization; response to ATP; response to carbohydrate stimulus; response to hypoxia; sensory perception of sound; sensory perception of taste; skeletal muscle fiber development; urinary bladder smooth muscle contraction

Disease: Deafness, Autosomal Dominant 41

Research Articles on P2RX2

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Product Notes

The P2RX2 p2rx2 (Catalog #AAA6165688) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's P2RX2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the P2RX2 p2rx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "P2RX2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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