Mouse O-GlcNAc Monoclonal Antibody | anti-O-GlcNAc antibody
O-GlcNAc antibody (mAb)(Clone CTD110.6)
Reactivity
Not Species Specific
Applications
Immunoprecipitation, Western Blot
Purity
IgM purification
Synonyms
O-GlcNAc; Monoclonal Antibody; O-GlcNAc antibody (mAb)(Clone CTD110.6); anti-O-GlcNAc antibody
Host
Mouse
Reactivity
Not Species Specific
Clonality
Monoclonal
Isotype
IgM
Clone Number
CTD110.6
Purity/Purification
IgM purification
Form/Format
Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Concentration
1ug/ul (varies by lot)
Applicable Applications for anti-O-GlcNAc antibody
Immunoprecipitation (IP), Western Blot (WB)
Conjugation
Acetylated
Immunogen
This antibody was raised against a peptide containing O-GlcNAc-serine. This antibody recognizes single O-GlcNAc residues in b-O-glycosidic linkage to serine and threonine.
Preparation and Storage
Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20 degree C for up to 2 years. Keep all reagents on ice when not in storage.1ug/ul
Related Product Information for anti-O-GlcNAc antibody
Short Description: Our O-GlcNAc antibody (mAb)(Clone CTD110.6) was raised in a Mouse host. It has been validated for use in Immunoprecipitation and Western blot; the sequence is not species specific so it should react with a wide range of sample types.
Background: O-GlcNAc (b-O-linked N-acetylglucosamine) is a ubiquitous and dynamic post-translational modification present on numerous cytoplasmic and nuclear proteins and is thought to play a regulatory role in numerous cellular processes including homeostatic mechanisms and gene expression. OGT (O-linked N-acetylglucosamine (GlcNAc) transferase) catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residues whereas OGA/O-GlcNAcase (O-linked N-acetylglucosamine (GlcNAc)-ase) is a glycosidase that removes O-GlcNAc. O-GlcNAc modifications have been described to directly regulate the activities of a variety of transcription factors including Sp1, estrogen receptors, STAT5, NF-kB, p53, YY1, Elf-1, c-Myc, Rb, PDX-1, CREB, fork-head, and others. In addition, RNA polymerase II and the basal transcription factors are also extensively modified by O-GlcNAc. O-GlcNAc modification has been reported to suppress or enhance transcription, depending on the promoter and other associated proteins.
Background: O-GlcNAc (b-O-linked N-acetylglucosamine) is a ubiquitous and dynamic post-translational modification present on numerous cytoplasmic and nuclear proteins and is thought to play a regulatory role in numerous cellular processes including homeostatic mechanisms and gene expression. OGT (O-linked N-acetylglucosamine (GlcNAc) transferase) catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residues whereas OGA/O-GlcNAcase (O-linked N-acetylglucosamine (GlcNAc)-ase) is a glycosidase that removes O-GlcNAc. O-GlcNAc modifications have been described to directly regulate the activities of a variety of transcription factors including Sp1, estrogen receptors, STAT5, NF-kB, p53, YY1, Elf-1, c-Myc, Rb, PDX-1, CREB, fork-head, and others. In addition, RNA polymerase II and the basal transcription factors are also extensively modified by O-GlcNAc. O-GlcNAc modification has been reported to suppress or enhance transcription, depending on the promoter and other associated proteins.
Product Categories/Family for anti-O-GlcNAc antibody
NCBI and Uniprot Product Information
Protein Family
Similar Products
Product Notes
The O-GlcNAc (Catalog #AAA388903) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The O-GlcNAc antibody (mAb)(Clone CTD110.6) reacts with Not Species Specific and may cross-react with other species as described in the data sheet. AAA Biotech's O-GlcNAc can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP), Western Blot (WB). Researchers should empirically determine the suitability of the O-GlcNAc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "O-GlcNAc, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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