Western Blot (WB)
(Western Blot detection against Immunogen (34.76kD).)
Mouse anti-Human NEUROG1 Monoclonal Antibody | anti-NEUROG1 antibody
NEUROG1 (Neurogenin 1, Neurogenin-1, NGN-1, Class A Basic Helix-loop-helix Protein 6, bHLHa6, Neurogenic Basic-helix-loop-helix Protein, Neurogenic Differentiation Factor 3, NeuroD3, BHLHA6, NEUROD3, NGN, NGN1)
Gene Names
NEUROG1; AKA; ngn1; Math4C; bHLHa6; NEUROD3
Reactivity
Human
Applications
ELISA, Western Blot, Immunofluorescence
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
NEUROG1; Monoclonal Antibody; NEUROG1 (Neurogenin 1; Neurogenin-1; NGN-1; Class A Basic Helix-loop-helix Protein 6; bHLHa6; Neurogenic Basic-helix-loop-helix Protein; Neurogenic Differentiation Factor 3; NeuroD3; BHLHA6; NEUROD3; NGN; NGN1); Anti -NEUROG1 (Neurogenin 1; anti-NEUROG1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
4A2
Specificity
Recognizes human NEUROG1.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
SEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRFAYNYIWALAETLRLADQGLPGGGARER
Applicable Applications for anti-NEUROG1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF)
Application Notes
Suitable for use in Immunofluorescence, ELISA and Western Blot.
Dilution: Immunofluorescence: 50ug/ml
Dilution: Immunofluorescence: 50ug/ml
Immunogen
Partial recombinant corresponding to aa82-163 from human NEUROG1 (NP_006152) with GST tag. MW of the GST tag alone is 26kD.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot detection against Immunogen (34.76kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (34.76kD).)
Western Blot (WB)
(NEUROG1 monoclonal antibody Western Blot analysis of NEUROG1 expression in Hela NE)
Western Blot (WB)
(NEUROG1 monoclonal antibody Western Blot analysis of NEUROG1 expression in Hela NE)
Immunofluorescence (IF)
(Immunofluorescence of monoclonal antibody to NEUROG1 on HeLa cell. [antibody concentration 50ug/ml])
Immunofluorescence (IF)
(Immunofluorescence of monoclonal antibody to NEUROG1 on HeLa cell. [antibody concentration 50ug/ml])
Related Product Information for anti-NEUROG1 antibody
Neurogenin-1 appears to mediate neuronal differentiation. It requires dimerisation with another basic-helix-loop-helix protein for efficient DNA binding. Its expression is restricted to the embryonic nervous system.
Product Categories/Family for anti-NEUROG1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,718 Da
NCBI Official Full Name
neurogenin-1
NCBI Official Synonym Full Names
neurogenin 1
NCBI Official Symbol
NEUROG1
NCBI Official Synonym Symbols
AKA; ngn1; Math4C; bHLHa6; NEUROD3
NCBI Protein Information
neurogenin-1; NGN-1; neurogenic differentiation 3; neurogenic differentiation factor 3; class A basic helix-loop-helix protein 6; neurogenic basic-helix-loop-helix protein
UniProt Protein Name
Neurogenin-1
Protein Family
UniProt Gene Name
NEUROG1
UniProt Synonym Gene Names
BHLHA6; NEUROD3; NGN; NGN1; NGN-1; bHLHa6; NeuroD3
UniProt Entry Name
NGN1_HUMAN
Uniprot Description
neurogenin 1: Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis.
Protein type: DNA-binding; Cell development/differentiation; Transcription factor
Chromosomal Location of Human Ortholog: 5q23-q31
Cellular Component: perikaryon; nucleus
Molecular Function: protein dimerization activity; DNA binding; chromatin binding; transcription factor activity
Biological Process: regulation of transcription from RNA polymerase II promoter; neuron differentiation; nervous system development; inner ear morphogenesis; cell fate commitment; transcription, DNA-dependent; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of neuron differentiation; positive regulation of exit from mitosis
Research Articles on NEUROG1
Similar Products
Product Notes
The NEUROG1 neurog1 (Catalog #AAA6002344) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NEUROG1 (Neurogenin 1, Neurogenin-1, NGN-1, Class A Basic Helix-loop-helix Protein 6, bHLHa6, Neurogenic Basic-helix-loop-helix Protein, Neurogenic Differentiation Factor 3, NeuroD3, BHLHA6, NEUROD3, NGN, NGN1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NEUROG1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF). Suitable for use in Immunofluorescence, ELISA and Western Blot. Dilution: Immunofluorescence: 50ug/ml. Researchers should empirically determine the suitability of the NEUROG1 neurog1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: SEALLHSLRR SRRVKANDRE RNRMHNLNAA LDALRSVLPS FPDDTKLTKI ETLRFAYNYI WALAETLRLA DQGLPGGGAR ER. It is sometimes possible for the material contained within the vial of "NEUROG1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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