anti-Human NCAM (CD56) Monoclonal Antibody
Mouse anti NCAM (CD56)
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Immunoprecipitation
Synonyms
NCAM (CD56); Monoclonal Antibody; Mouse anti NCAM (CD56); anti-NCAM (CD56) antibody
Host
Mouse (Balb/c)
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
NKI-nbl-1
Specificity
Different antibodies recognize a heterodimeric glycoprotein of 145, 185 kD which has been identified as NCAM (Neural Cell Adhesion Module). Two major epitopes have been defined, NKI-nbl-1 (art. nr. MUB1321S and MUB1321P) reacts with epitope 1 and 123C3 (art. nr. MUB1301S and MUB1301P) reacts with epitope 2.
Form/Format
Each vial contains 100 ul 1 mg/ml purified monoclonal antibody in PBS containing 0.09% sodium azide.
Applicable Applications for anti-NCAM (CD56) antibody
Immunofluorescence (IF), Immunohistochemistry (IHC) (frozen), Immunoprecipitation (IP)
Application Notes
NKI-nbl-1 is useful for immunofluorescence, immunoprecipitation and immunohistochemistry on frozen tissues. Optimal antibody dilution should be determined by titRation.
Source Note
NKI-NBl-1 is a Mouse monoclonal IgG1 antibody derived by fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with neuroblastoma cell line CHP-212.
Preparation and Storage
Store at 4 degree C, or in small aliquots at -20 degree C.
Related Product Information for anti-NCAM (CD56) antibody
NCAM, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig)-like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be geneRated by alternative splicing and by posttranslational modifiCations, such as sialylation. During sialylation, polysialic acid (PSA) carbohydRates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins.
Product Categories/Family for anti-NCAM (CD56) antibody
References
K. Moolenaar et al.Cancer Research 50, 1102-1106, Feb15, 1990.
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Product Notes
The NCAM (CD56) (Catalog #AAA570285) is an Antibody produced from Mouse (Balb/c) and is intended for research purposes only. The product is available for immediate purchase. The Mouse anti NCAM (CD56) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NCAM (CD56) can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC) (frozen), Immunoprecipitation (IP). NKI-nbl-1 is useful for immunofluorescence, immunoprecipitation and immunohistochemistry on frozen tissues. Optimal antibody dilution should be determined by titRation. Researchers should empirically determine the suitability of the NCAM (CD56) for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NCAM (CD56), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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