Mouse anti-Human NAGLU Monoclonal Antibody | anti-Naglu antibody
NAGLU (Alpha-N-acetylglucosaminidase, N-acetyl-alpha-glucosaminidase, NAG, UFHSD1) (Azide Free)
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
NAGLU; Monoclonal Antibody; NAGLU (Alpha-N-acetylglucosaminidase; N-acetyl-alpha-glucosaminidase; NAG; UFHSD1) (Azide Free); Anti -NAGLU (Alpha-N-acetylglucosaminidase; anti-Naglu antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
11C455
Specificity
Recognizes human NAGLU.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
Applicable Applications for anti-Naglu antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1:500-1:1,000
ELISA: 1ug/ml-3ng/ml
Dilution: Western Blot: 1:500-1:1,000
ELISA: 1ug/ml-3ng/ml
Immunogen
Recombinant protein corresponding to aa644-743 of human NAGLU.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-Naglu antibody
This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate. [provided by RefSeq]
Product Categories/Family for anti-Naglu antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
82,610 Da
NCBI Official Full Name
Naglu
NCBI Official Synonym Full Names
alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)
NCBI Official Symbol
Naglu
NCBI Protein Information
alpha-N-acetylglucosaminidase; OTTMUSP00000002515; N-acetyl-glucosaminidase; alpha-N-acetylglucosaminidase, lysosomal
UniProt Protein Name
Naglu
Protein Family
UniProt Gene Name
Naglu
UniProt Entry Name
O54752_MOUSE
Uniprot Description
NAGLU: Involved in the degradation of heparan sulfate. Defects in NAGLU are the cause of mucopolysaccharidosis type 3B (MPS3B); also known as Sanfilippo syndrome B. MPS3B is a form of mucopolysaccharidosis type 3, an autosomal recessive lysosomal storage disease due to impaired degradation of heparan sulfate. MPS3 is characterized by severe central nervous system degeneration, but only mild somatic disease. Onset of clinical features usually occurs between 2 and 6 years; severe neurologic degeneration occurs in most patients between 6 and 10 years of age, and death occurs typically during the second or third decade of life.
Protein type: Glycan Metabolism - glycosaminoglycan degradation; EC 3.2.1.50; Hydrolase
Molecular Function: alpha-N-acetylglucosaminidase activity
Biological Process: locomotor rhythm; retinal rod cell development; lysosome organization and biogenesis; inner ear receptor cell development; cerebellar Purkinje cell layer development; middle ear morphogenesis
Research Articles on Naglu
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Product Notes
The Naglu naglu (Catalog #AAA632346) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NAGLU (Alpha-N-acetylglucosaminidase, N-acetyl-alpha-glucosaminidase, NAG, UFHSD1) (Azide Free) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NAGLU can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1:500-1:1,000 ELISA: 1ug/ml-3ng/ml. Researchers should empirically determine the suitability of the Naglu naglu for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NAGLU, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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