Mouse N-Acetyltransferase 6 Monoclonal Antibody | anti-NAT6 antibody

Mouse Anti Human N-Acetyltransferase 6

Cat. Num. AAA140286

• Gene Names: NAT6; FUS2; FUS-2
• Applications: ELISA, Western Blot
• Purity: NAT6 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
• Synonyms: N-Acetyltransferase 6; Monoclonal Antibody; Mouse Anti Human N-Acetyltransferase 6; NAT6 Antibody; Mouse Anti Human; Protein fusion-2; FUS2; FUS-2; NAT6; N-acetyltransferase 6; Protein fus-2; anti-NAT6 antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1 heavy chain and kappa light chain
• Clone Number: PAT2F4AT
• Purity/Purification: NAT6 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
• Form/Format: 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
• Sequence Length: 286

• Applicable Applications for anti-NAT6 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: NAT6 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot and Immunofluorescence analysis is 1:500 ~ 1000. Recommended starting dilution is 1:500.
• Immunogen: Anti-human NAT6 mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NAT6 amino acids 1-308 purified from E Coli.
• Preparation and Storage: For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.; 12 months at -20 degree C. 1 month at 4 degree C.

Related Product Information for anti-NAT6 antibody

Introduction: NAT6 is an enzyme that catalyzes the transfer of acetyl groups from acetyl-CoA to acrylamines. NAT6 is located mainly in the cytoplasm and its activity has been recognized by its feasibility to acetylate the N-terminus of proteins using a ping-pong-like mechanism and by its substrate specificity. Given that the NAT6 gene maps to the chromosomal region 3p21.3, which includes at least one tumor suppressor gene, the function of NAT6 plays an important role in cancer.

Product Categories/Family for anti-NAT6 antibody

Monoclonal Antibodies; Anti-Human Enzymes; Monoclonal Antibodies; Anti Human Enzyme

NCBI and Uniprot Product Information

• NCBI GI #: 318037386
• NCBI GeneID: 24142
• NCBI Accession #: NP_001186945.1
• NCBI GenBank Nucleotide #: NM_001200016.1
• Molecular Weight: 33,831 Da
• NCBI Official Full Name: N-acetyltransferase 6 isoform 2
• NCBI Official Synonym Full Names: N-acetyltransferase 6 (GCN5-related)
• NCBI Official Symbol: NAT6
• NCBI Official Synonym Symbols: FUS2; FUS-2
• NCBI Protein Information: N-acetyltransferase 6; protein fusion-2
• UniProt Protein Name: N-acetyltransferase 6
• Protein Family: N-acetyltransferase
• UniProt Gene Name: NAT6
• UniProt Synonym Gene Names: FUS2; Protein fus-2
• UniProt Entry Name: NAT6_HUMAN

NCBI Description

This gene encodes a member of the N-acetyltransferase family. N-acetyltransferases modify proteins by transferring acetyl groups from acetyl CoA to the N-termini of protein substrates. The encoded protein is a cytoplasmic N-acetyltransferase with a substrate specificity for proteins with an N-terminal methionine. This gene is located in the tumor suppressor gene region on chromosome 3p21.3 and the encoded protein may play a role in cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed. This gene overlaps and is on the same strand as hyaluronoglucosaminidase 3, and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]

Uniprot Description

NAT6: Seems to be involved in N-acetylation. Acts on peptides with a N-terminal Met followed by Asp/Glu/Asn. May act as a tumor suppressor. Belongs to the acetyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - tyrosine; EC 2.3.1.-; Amino Acid Metabolism - phenylalanine; Lipid Metabolism - glycerophospholipid; Tumor suppressor; Secondary Metabolites Metabolism - limonene and pinene degradation; Acetyltransferase

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: cytoplasm

Molecular Function: N-acetyltransferase activity

Biological Process: metabolic process