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Western Blot (WB) (TAGLN2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TAGLN2 antibody detected the TAGLN2 protein (arrow).)

Rabbit anti-Human TAGLN2 Polyclonal Antibody | anti-TAGLN2 antibody

TAGLN2, CT (TAGLN2, KIAA0120, Transgelin-2, Epididymis tissue protein Li 7e, SM22-alpha homolog) (AP)

Gene Names
TAGLN2; HA1756
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
TAGLN2; Polyclonal Antibody; CT (TAGLN2; KIAA0120; Transgelin-2; Epididymis tissue protein Li 7e; SM22-alpha homolog) (AP); SM22-alpha homolog; anti-TAGLN2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-TAGLN2 antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes
IHC: 1:10-50
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
TAGLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-165 amino acids from the C-terminal region of human TAGLN2.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(TAGLN2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TAGLN2 antibody detected the TAGLN2 protein (arrow).)

Western Blot (WB) (TAGLN2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TAGLN2 antibody detected the TAGLN2 protein (arrow).)

Immunohistochemistry (IHC)

(TAGLN2 Antibody (C-term) (AP14063b)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TAGLN2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (TAGLN2 Antibody (C-term) (AP14063b)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TAGLN2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-TAGLN2 antibody
The protein encoded by this gene is a homolog of the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The function of this protein has not yet been determined.
Product Categories/Family for anti-TAGLN2 antibody
References
Rho, J.H., et al. J. Proteome Res. 8(12):5610-5618(2009). Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007): Wang, L., et al. J. Mol. Med. 83(10):812-821(2005). Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003). Hoja, M.R., et al. Exp. Cell Res. 259(1):239-246(2000).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,454 Da
NCBI Official Full Name
transgelin-2 isoform b
NCBI Official Synonym Full Names
transgelin 2
NCBI Official Symbol
TAGLN2
NCBI Official Synonym Symbols
HA1756
NCBI Protein Information
transgelin-2
UniProt Protein Name
Transgelin-2
Protein Family
UniProt Gene Name
TAGLN2
UniProt Synonym Gene Names
KIAA0120
UniProt Entry Name
TAGL2_HUMAN

NCBI Description

The protein encoded by this gene is similar to the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The specific function of this protein has not yet been determined, although it is thought to be a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]

Uniprot Description

TAGLN2: a cytoskeletal protein of the calponin family. One of the earliest markers of differentiated smooth muscle. Expressed in the smooth, cardiac, and skeletal muscle cells during early embryogenesis. Becomes restricted to vascular and visceral smooth muscle cells in late fetal development and adulthood. Its expression is abolished by activated Ras. Ras-dependent and Ras-independent mechanisms can cause the down-regulation of transgelin in breast and colon cancer cells lines and tumor samples.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1q21-q25

Cellular Component: vesicle

Molecular Function: actin filament binding; protein binding

Biological Process: epithelial cell differentiation

Research Articles on TAGLN2

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Product Notes

The TAGLN2 tagln2 (Catalog #AAA6353479) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TAGLN2, CT (TAGLN2, KIAA0120, Transgelin-2, Epididymis tissue protein Li 7e, SM22-alpha homolog) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TAGLN2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB). IHC: 1:10-50 ELISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the TAGLN2 tagln2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAGLN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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