Mouse anti-Human MUM1 Monoclonal Antibody | anti-MUM1 antibody

Mouse Monoclonal [clone 4G10] (IgG1) to Human MUM1

Cat. Num. AAA246439

• Gene Names: MUM1; MUM-1; EXPAND1; HSPC211
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot, ELISA
• Purity: Ascites
• Synonyms: MUM1; Monoclonal Antibody; Mouse Monoclonal [clone 4G10] (IgG1) to Human MUM1; Anti-MUM1 Antibody (clone 4G10) IHC-plus; EXPAND1; HSPC211; MUM-1; Protein expandere; Human MUM1; anti-MUM1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 4G10
• Specificity: Human MUM1
• Purity/Purification: Ascites
• Form/Format: Ascitic fluid, 0.03% sodium azide
• Sequence Length: 59128983

• Applicable Applications for anti-MUM1 antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
• Application Notes: ELISA, IHC-P (1:200), WB (1:500 - 1:2000)
• Target Species: Human
• Immunogen Description: Purified recombinant fragment of human MUM1 expressed in E Coli.
• Immunogen: MUM1 antibody was raised against purified recombinant fragment of human MUM1 expressed in E Coli.
• Preparation and Storage: Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.

Immunohistochemistry (IHC)

(Anti-MUM1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.)

Immunohistochemistry (IHC)

(Anti-MUM1 antibody IHC of human small intestine, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.)

Immunohistochemistry (IHC)

(Anti-MUM1 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.)

NCBI and Uniprot Product Information

• NCBI GI #: 224589810
• NCBI GeneID: 84939
• NCBI Accession #: NC_000019.9
• NCBI GenBank Nucleotide #: NC_000019.9
• Molecular Weight: 80,700 Da
• NCBI Official Full Name: Homo sapiens chromosome 19, GRCh37.p13 Primary Assembly
• NCBI Official Synonym Full Names: melanoma associated antigen (mutated) 1
• NCBI Official Symbol: MUM1
• NCBI Official Synonym Symbols: MUM-1; EXPAND1; HSPC211
• NCBI Protein Information: PWWP domain-containing protein MUM1; protein expandere; melanoma ubiquitous mutated protein; mutated melanoma-associated antigen 1
• UniProt Protein Name: PWWP domain-containing protein MUM1
• Protein Family: PWWP domain-containing protein
• UniProt Gene Name: MUM1
• UniProt Synonym Gene Names: EXPAND1; MUM-1
• UniProt Entry Name: MUM1_HUMAN

Uniprot Description

MUM1: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage. Belongs to the MUM1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell surface

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: nucleus

Molecular Function: protein binding; nucleosome binding

Biological Process: establishment and/or maintenance of chromatin architecture; DNA repair