Rabbit anti-Human MS4A1 Monoclonal Antibody | anti-MS4A1 antibody
Rabbit anti Human MS4A1 Monoclonal Antibody
Gene Names
Ms4a1; Cd20; Ly-44; Ms4a2; AA960661
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Synonyms
MS4A1 ; Monoclonal Antibody; Rabbit anti Human MS4A1 Monoclonal Antibody; anti-MS4A1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Sequence Length
291
Applicable Applications for anti-MS4A1 antibody
Flow Cyometry (FC/FACS)
Application Notes
Flow Cytometry: 0.5-2 mug/Test
Immunogen
Human CD20 Transfected CHO Cells
Buffer
0.2 mum filtered solution in PBS with 5% trehalose
Preparation and Storage
This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-MS4A1 antibody
CD20 (membrane-spanning 4-domains, subfamily A, member 1), also known as MS4A1, is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. CD20/MS4A1 is expressed on all stages of B cell development except the first and last. CD20/MS4A1 is present from pre-pre B cells through memory cells, but not on either pro-B cells or plasma cells. It is a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. CD20/MS4A1may be involved in the regulation of B-cell activation and proliferation. Defects in CD20/MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5). CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
31,958 Da
NCBI Official Full Name
Ms4a1
NCBI Official Synonym Full Names
membrane-spanning 4-domains, subfamily A, member 1
NCBI Official Symbol
Ms4a1
NCBI Official Synonym Symbols
Cd20; Ly-44; Ms4a2; AA960661
NCBI Protein Information
B-lymphocyte antigen CD20
UniProt Protein Name
Membrane-spanning 4-domains, subfamily A, member 1, isoform CRA_b
UniProt Gene Name
Ms4a1
UniProt Entry Name
Q542S5_MOUSE
Research Articles on MS4A1
Similar Products
Product Notes
The MS4A1 ms4a1 (Catalog #AAA2544140) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human MS4A1 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MS4A1 can be used in a range of immunoassay formats including, but not limited to, Flow Cyometry (FC/FACS). Flow Cytometry: 0.5-2 mug/Test. Researchers should empirically determine the suitability of the MS4A1 ms4a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MS4A1 , Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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