Immunohistochemistry (IHC)
(Anti-MPS1/TTK antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Mouse anti-Human MPS1/TTK Monoclonal Antibody | anti-MPS1/TTK antibody
Anti-MPS1/TTK Antibody (clone 3G7)
WB: 1:500-1:1000
Aliquot to avoid repeated freezing and thawing.
Immunohistochemistry (IHC)
(Anti-MPS1/TTK antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Immunohistochemistry (IHC)
(Anti-MPS1/TTK antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Western Blot (WB)
(TTK monoclonal antibody (M01), clone 3G7. Western Blot analysis of TTK expression in HeLa.)
Western Blot (WB)
(TTK monoclonal antibody (M01), clone 3G7. Western Blot analysis of TTK expression in HeLa.)
Western Blot (WB)
(Western Blot analysis of TTK expression in transfected 293T cell line by TTK monoclonal antibody (M01), clone 3G7.Lane 1: TTK transfected lysate(97.1 KDa).Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of TTK expression in transfected 293T cell line by TTK monoclonal antibody (M01), clone 3G7.Lane 1: TTK transfected lysate(97.1 KDa).Lane 2: Non-transfected lysate.)
Western Blot (WB)
(TTK monoclonal antibody (M01), clone 3G7 Western Blot analysis of TTK expression in K-562.)
Western Blot (WB)
(TTK monoclonal antibody (M01), clone 3G7 Western Blot analysis of TTK expression in K-562.)
ELISA (EIA)
(Detection limit for recombinant GST tagged TTK is approximately 0.3 ng/ml as a capture antibody.)
ELISA (EIA)
(Detection limit for recombinant GST tagged TTK is approximately 0.3 ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
Uniprot Description
Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.
Research Articles on MPS1/TTK
Similar Products
Product Notes
The MPS1/TTK ttk (Catalog #AAA2401040) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-MPS1/TTK Antibody (clone 3G7) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MPS1/TTK can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 10 ug/ml WB: 1:500-1:1000. Researchers should empirically determine the suitability of the MPS1/TTK ttk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MPS1/TTK, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
