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Testing Data

Mouse anti-Mouse MHC Class 1, H2, Db, alpha3 Monoclonal Antibody

MHC Class 1, H2, Db, alpha3 (PE)

Reactivity
Mouse
Applications
Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Purified
Purified
Synonyms
MHC Class 1; H2; Db; alpha3; Monoclonal Antibody; alpha3 (PE); Anti -MHC Class 1; anti-MHC Class 1; alpha3 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
28-14-8
Specificity
Recognizes an epitope in the alpha3 domain of H-2Db.
Purity/Purification
Purified
Purified
Form/Format
Supplied as a liquid in PBS, 0.1% sodium azide and a stabilizing agent. Conjugated to PE.
Applicable Applications for anti-MHC Class 1, H2, Db, alpha3 antibody
Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
Flow cytometry, , Immunohistochemistry (frozen tissue sections), , Complement-mediated cytotoxicity
Dilution: Flow Cytometry: 0.5ug/10e6 cells
Immunogen
C3H.SW mouse splenocytes
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20 degree C or colder. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Testing Data

Testing Data
Related Product Information for anti-MHC Class 1, H2, Db, alpha3 antibody
MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic alpha chains noncovalently associated with the invariant beta2-microglobulin.3, 4 These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells.5 MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny.3, 6 This antibody binds to the alpha3 domain of H-2Db in the presence or absence of beta2 microglobulin.7,8
Product Categories/Family for anti-MHC Class 1, H2, Db, alpha3 antibody

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Product Notes

The MHC Class 1, H2, Db, alpha3 (Catalog #AAA603307) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MHC Class 1, H2, Db, alpha3 (PE) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MHC Class 1, H2, Db, alpha3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). Flow cytometry,, Immunohistochemistry (frozen tissue sections),, Complement-mediated cytotoxicity Dilution: Flow Cytometry: 0.5ug/10e6 cells. Researchers should empirically determine the suitability of the MHC Class 1, H2, Db, alpha3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MHC Class 1, H2, Db, alpha3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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