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Mouse anti-Human Methionine Sulfoxide Reductase A (MSRA) Monoclonal Antibody | anti-MSRA antibody

APC-Linked Monoclonal Antibody to Methionine Sulfoxide Reductase A (MSRA)

Gene Names
MSRA; PMSR
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Protein A + Protein G Affinity Chromatography
Synonyms
Methionine Sulfoxide Reductase A (MSRA); Monoclonal Antibody; APC-Linked Monoclonal Antibody to Methionine Sulfoxide Reductase A (MSRA); PMSR; Peptide Methionine Sulfoxide Reductase; Protein-methionine-S-oxide reductase; anti-MSRA antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a Kappa
Clone Number
C4
Specificity
The antibody is a mouse monoclonal antibody raised against MSRA. It has been selected for its ability to recognize MSRA in immunohistochemical staining and western blotting.
Purity/Purification
Protein A + Protein G Affinity Chromatography
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Concentration
>=100ug/ml (varies by lot)
Sequence
Ala27~Lys235
Applicable Applications for anti-MSRA antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Immunogen Sequence
Ala27~Lys235
Cross Reactivity
Human
Conjugation
APC
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Product Categories/Family for anti-MSRA antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,627 Da
NCBI Official Full Name
mitochondrial peptide methionine sulfoxide reductase isoform b
NCBI Official Synonym Full Names
methionine sulfoxide reductase A
NCBI Official Symbol
MSRA
NCBI Official Synonym Symbols
PMSR
NCBI Protein Information
mitochondrial peptide methionine sulfoxide reductase; cytosolic methionine-S-sulfoxide reductase; peptide Met(O) reductase; peptide met (O) reductase; peptide-methionine (S)-S-oxide reductase
UniProt Protein Name
Mitochondrial peptide methionine sulfoxide reductase
UniProt Gene Name
MSRA
UniProt Synonym Gene Names
Peptide Met(O) reductase; PMSR
UniProt Entry Name
MSRA_HUMAN

NCBI Description

This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein functions in the repair of oxidatively damaged proteins to restore biological activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Uniprot Description

MSRA: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Belongs to the MsrA Met sulfoxide reductase family. 5 isoforms of the human protein are produced by alternative promoter.

Protein type: EC 1.8.4.11; Oxidoreductase

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: nucleoplasm; mitochondrion; membrane; cytoplasm; actin cytoskeleton

Molecular Function: peptide-methionine-(S)-S-oxide reductase activity

Biological Process: protein repair; protein modification process; methionine metabolic process; response to oxidative stress

Research Articles on MSRA

Similar Products

Product Notes

The MSRA msra (Catalog #AAA2120138) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The APC-Linked Monoclonal Antibody to Methionine Sulfoxide Reductase A (MSRA) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Methionine Sulfoxide Reductase A (MSRA) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the MSRA msra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Ala27~Lys2 35. It is sometimes possible for the material contained within the vial of "Methionine Sulfoxide Reductase A (MSRA), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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