Mouse anti-Human MAT1A Monoclonal Antibody | anti-mat1a antibody

MAT1A (S-adenosylmethionine Synthase Isoform Type-1, AdoMet Synthase 1, Methionine Adenosyltransferase 1, MAT 1, Methionine Adenosyltransferase I/III, MAT-I/III, AMS1, MATA1)

Cat. Num. AAA6010013

• Gene Names: mat1a; zgc:55442; wu:fi35e01
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunoprecipitation
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: MAT1A; Monoclonal Antibody; MAT1A (S-adenosylmethionine Synthase Isoform Type-1; AdoMet Synthase 1; Methionine Adenosyltransferase 1; MAT 1; Methionine Adenosyltransferase I/III; MAT-I/III; AMS1; MATA1); Anti -MAT1A (S-adenosylmethionine Synthase Isoform Type-1; anti-mat1a antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2a,k
• Clone Number: 4D11
• Specificity: Recognizes human MAT1A.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MNGPVDGLCDHSLSEGVFMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSMAMVDYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYATDETEECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISVQHNEDITLEEMRRALKEQVIRAVVPAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPRKLVF

• Applicable Applications for anti-mat1a antibody: ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)
• Application Notes: Suitable for use in Western Blot, ELISA and Immunoprecipitation.
• Immunogen: Full length recombinant corresponding to aa1-395 from human MAT1A (AAH18359) with GST tag. MW of the GST tag alone is 26kD.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (69.19kD).)

Western Blot (WB)

(Western Blot analysis of MAT1A expression in transfected 293T cell line by MAT1A monoclonal antibody.|Lane 1: MAT1A transfected lysate (43.6kD).|Lane 2: Non-transfected lysate.)

Immunoprecipitation (IP)

(Immunoprecipitation of MAT1A transfected lysate using MAT1A monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with MAT1A monoclonal antibody.)

Related Product Information for anti-mat1a antibody

MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. Mutations in this gene are associated with methionine adenosyltransferase deficiency.

Product Categories/Family for anti-mat1a antibody

Antibodies; Abs to Enzymes; Synthase

NCBI and Uniprot Product Information

• NCBI GI #: 182888984
• NCBI GeneID: 334195
• NCBI Official Full Name: Mat1a protein
• NCBI Official Synonym Full Names: methionine adenosyltransferase I, alpha
• NCBI Official Symbol: mat1a
• NCBI Official Synonym Symbols: zgc:55442; wu:fi35e01
• NCBI Protein Information: S-adenosylmethionine synthase isoform type-1
• Protein Family: S-adenosylmethionine synthase

Uniprot Description

Catalyzes the formation of S-adenosylmethionine from methionine and ATP.