Rabbit MAT1A Polyclonal Antibody | anti-MAT1A antibody

MAT1A Polyclonal Antibody

Cat. Num. AAA2555784

• Gene Names: MAT1A; MAT; SAMS; MATA1; SAMS1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity Purification
• Synonyms: MAT1A; Polyclonal Antibody; MAT1A Polyclonal Antibody; AdoMet; AdoMet synthetase 1; AI046368; Ams; MAT; MAT I/III; MATA1; Methionine adenosyltransferase 1; Methionine adenosyltransferase I; alpha; Methionine adenosyltransferase I/III; MGC108563; S adenosylmethionine synthetase isoform type 1; SADE; SAMS; SAMS1; anti-MAT1A antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 395

• Applicable Applications for anti-MAT1A antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000; IHC: 1:50-1:200
• Immunogen: Recombinant protein of human MAT1A
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using MAT1A antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver injury using MAT1A antibody.)

Related Product Information for anti-MAT1A antibody

This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.

Product Categories/Family for anti-MAT1A antibody

Cancer; Metabolism; Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 4557737
• NCBI GeneID: 4143
• NCBI Accession #: NP_000420.1
• NCBI GenBank Nucleotide #: NM_000429.3
• UniProt Accession #: Q00266; Q5QP09; D3DWD5
• Molecular Weight: Calculated: 43kDa; Observed: 44kDa
• NCBI Official Full Name: S-adenosylmethionine synthase isoform type-1
• NCBI Official Synonym Full Names: methionine adenosyltransferase 1A
• NCBI Official Symbol: MAT1A
• NCBI Official Synonym Symbols: MAT; SAMS; MATA1; SAMS1
• NCBI Protein Information: S-adenosylmethionine synthase isoform type-1
• UniProt Protein Name: S-adenosylmethionine synthase isoform type-1
• Protein Family: S-adenosylmethionine synthase
• UniProt Gene Name: MAT1A
• UniProt Synonym Gene Names: AMS1; MATA1; AdoMet synthase 1; MAT 1; MAT-I/III

NCBI Description

This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. [provided by RefSeq, Jul 2008]

Uniprot Description

Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.