Western Blot (WB)
(Western Blot detection against Immunogen (66.15kD).)
Mouse anti-Human MA2 Monoclonal Antibody | anti-MA2 antibody
MA2 (Paraneoplastic Antigen Ma2, 40kD Neuronal Protein, PNMA2, Onconeuronal Antigen Ma2, Paraneoplastic Neuronal Antigen MM2, KIAA0883) (Biotin)
Gene Names
PNMA2; MA2; MM2; RGAG2
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
MA2; Monoclonal Antibody; MA2 (Paraneoplastic Antigen Ma2; 40kD Neuronal Protein; PNMA2; Onconeuronal Antigen Ma2; Paraneoplastic Neuronal Antigen MM2; KIAA0883) (Biotin); anti-MA2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
2C5
Specificity
Recognizes human PNMA2.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-MA2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length recombinant corresponding to aa1-364 from human PNMA2 (AAH62301) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQEVLQETLKSLGRYRLLGKIFRKQENANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPNQDTEFLERLNLFLEKEGQTVSGMFRALGQEGVSPATVPCISPELLAHLLGQAMAHAPQPLLPMRYRKLRVFSGSAVPAPEEESFEVWLEQATEIVKEWPVTEAEKKRWLAESLRGPALDLMHIVQADNPSISVEECLEAFKQVFGSLESRRTAQVRYLKTYQEEGEKVSAYVLRLETLLRRAVEKRAIPRRIADQVRLEQVMAGATLNQMLWCRLRELKDQGPPPSFLELMKVIREEEEEEASFENESIEEPEERDGYGRWNHEGDD
Conjugate
Biotin
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot detection against Immunogen (66.15kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (66.15kD).)
Testing Data
(Detection limit for recombinant GST tagged PNMA2 is ~1ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged PNMA2 is ~1ng/ml as a capture antibody.)
Related Product Information for anti-MA2 antibody
In patients with cancer, symptoms of limbic and brain-stem dysfunction may result from a para-neoplastic disorder. Two proteins, Ma1 and Ma2, were discovered by presence of autoantibodies against them. Antibodies to Ma1 and Ma2 proteins identify a paraneoplastic disorder that affects the limbic system, brain stem, and cerebellum. These autoantibodies were used to clone Ma2, which codes for a protein (Ma2) that was recognized by serum from the 10 patients, but not by serum from 344 control subjects. Ma2 was selectively expressed by normal brain tissue and by the testicular tumors of the patients. Ma2 shares homology with Ma1, a brain-testis-cancer gene related to other para-neoplastic syndromes and tumors.
Product Categories/Family for anti-MA2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
41,509 Da
NCBI Official Full Name
Homo sapiens paraneoplastic antigen MA2, mRNA
NCBI Official Synonym Full Names
PNMA family member 2
NCBI Official Symbol
PNMA2
NCBI Official Synonym Symbols
MA2; MM2; RGAG2
NCBI Protein Information
paraneoplastic antigen Ma2
Protein Family
Research Articles on MA2
Similar Products
Product Notes
The MA2 (Catalog #AAA6142776) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MA2 (Paraneoplastic Antigen Ma2, 40kD Neuronal Protein, PNMA2, Onconeuronal Antigen Ma2, Paraneoplastic Neuronal Antigen MM2, KIAA0883) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MA2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the MA2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MA2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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