Mouse Lys-63-specific deubiquitinase BRCC36 Monoclonal Antibody | anti-BRCC3 antibody
Mouse Anti Human Lys-63-specific deubiquitinase BRCC36
Gene Names
DEPDC1B; XTP1; BRCC3
Applications
ELISA, Western Blot
Purity
BRCC3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Synonyms
Lys-63-specific deubiquitinase BRCC36; Monoclonal Antibody; Mouse Anti Human Lys-63-specific deubiquitinase BRCC36; BRCC3 Antibody; Mouse Anti Human; BRCA1-A complex subunit BRCC36; BRISC complex subunit BRCC36; BRCA1/BRCA2-containing complex subunit 3; BRCA1/BRCA2-containing complex subunit 36; BRCC3; BRCC36; C6.1A; CXorf53; RP11-143H17.2; anti-BRCC3 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1 heavy chain and kappa light chain
Clone Number
PAT3B1AT
Purity/Purification
BRCC3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Form/Format
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Sequence Length
467
Applicable Applications for anti-BRCC3 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
BRCC3 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000 ~ 2000. Recommended starting dilution is 1:1000.
Immunogen
Anti-human BRCC3 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human BRCC3 amino acids 1-316 purified from E Coli.
Preparation and Storage
For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.
12 months at -20 degree C. 1 month at 4 degree C.
12 months at -20 degree C. 1 month at 4 degree C.
Related Product Information for anti-BRCC3 antibody
Introduction: BRCC3 is a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. BRCC3 is also thought to be involved in the cellular response to ionizing radiation and progression through the G2/M checkpoint.
Product Categories/Family for anti-BRCC3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54,726 Da
NCBI Official Full Name
DEP domain-containing protein 1B isoform 2
NCBI Official Synonym Full Names
DEP domain containing 1B
NCBI Official Symbol
DEPDC1B
NCBI Official Synonym Symbols
XTP1; BRCC3
NCBI Protein Information
DEP domain-containing protein 1B; HBV X-transactivated gene 8 protein; HBV XAg-transactivated protein 8; HBxAg transactivated protein 1; breast cancer cell 3
UniProt Protein Name
DEP domain-containing protein 1B
Protein Family
UniProt Gene Name
DEPDC1B
UniProt Synonym Gene Names
XTP8
UniProt Entry Name
DEP1B_HUMAN
Uniprot Description
DEPDC1B: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs; GAPs, Rac/Rho
Chromosomal Location of Human Ortholog: 5q12.1
Cellular Component: cytosol
Molecular Function: GTPase activator activity
Biological Process: cell migration; regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; positive regulation of Wnt receptor signaling pathway; positive regulation of GTPase activity
Research Articles on BRCC3
Similar Products
Product Notes
The BRCC3 depdc1b (Catalog #AAA140282) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Lys-63-specific deubiquitinase BRCC36 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). BRCC3 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000 ~ 2000. Recommended starting dilution is 1:1000. Researchers should empirically determine the suitability of the BRCC3 depdc1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lys-63-specific deubiquitinase BRCC36, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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