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Rat anti-Mouse Lymphocyte antigen 6C2, MACROPHAGE PRECURSOR CELLS Monoclonal Antibody | anti-Ly6c1 antibody

Lymphocyte antigen 6C2, MACROPHAGE PRECURSOR CELLS (Ly-6c)

Gene Names
Ly6c1; Ly6c; Ly-6C; Ly6c2; Ly-6C1; AA682074; AA959465
Reactivity
Mouse
Applications
Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Affinity Purified
Purified
Synonyms
Lymphocyte antigen 6C2; MACROPHAGE PRECURSOR CELLS; Monoclonal Antibody; MACROPHAGE PRECURSOR CELLS (Ly-6c); Anti -Lymphocyte antigen 6C2; anti-Ly6c1 antibody
Ordering
For Research Use Only!
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
9G221
Specificity
Recognizes mouse macrophage precursor cells in the mid-stage of their development (late CFU-M, monoblasts and monocytes).
Purity/Purification
Affinity Purified
Purified
Form/Format
Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
Applicable Applications for anti-Ly6c1 antibody
Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in Flow Cytometry and Immunohistochemistry.
Dilution: Flow Cytometry: 1:50
Immunohistochemistry: 1:50
The antigen is glutaraldehyde (0.05%) and paraformaldehyde (1%) resistant.
Immunogen
Mouse macrophage cell lines
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Ly6c1 antibody
The antigen is a 14kD surface protein which is very similar to Ly-6C and may be analogous to human CD59. It is inducible by IFN-alpha, IFN-beta and IFN-gamma. In tissue sections, the antigen is found on macrophage precursor subpopulations. In the bone marrow and hemopoietic islands of the lymphoid organs, and in the spleen. Activated macrophages in inflammatory tissues also express the related antigen. The monoclonal antibody also identifies activated macrophages in inflammatory tissues where the simultaneous use of the murine pan-macrophage marker BM8 (anti-F4/80) is recommended. In combination with an anti-mouse CD31/PECAM-1 antibody, can be used to evaluate the cellular composition in murine bone marrow (e.g. using flow cytometric analysis). Also detects a wide range of endothelial cells.
Product Categories/Family for anti-Ly6c1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,193 Da
NCBI Official Full Name
lymphocyte antigen 6C2
NCBI Official Synonym Full Names
lymphocyte antigen 6 complex, locus C1
NCBI Official Symbol
Ly6c1
NCBI Official Synonym Symbols
Ly6c; Ly-6C; Ly6c2; Ly-6C1; AA682074; AA959465
NCBI Protein Information
lymphocyte antigen 6C2; ly-6C2; Lymphocyte antigen Ly-6C; lymphocyte antigen 6 complex, locus C
UniProt Protein Name
Lymphocyte antigen 6C1
Protein Family
UniProt Gene Name
Ly6c1
UniProt Synonym Gene Names
Ly6c
UniProt Entry Name
LY6C1_MOUSE

Uniprot Description

LY6C1:

Cellular Component: membrane; plasma membrane; external side of plasma membrane

Research Articles on Ly6c1

Similar Products

Product Notes

The Ly6c1 ly6c1 (Catalog #AAA605460) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Lymphocyte antigen 6C2, MACROPHAGE PRECURSOR CELLS (Ly-6c) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Lymphocyte antigen 6C2, MACROPHAGE PRECURSOR CELLS can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). Suitable for use in Flow Cytometry and Immunohistochemistry. Dilution: Flow Cytometry: 1:50 Immunohistochemistry: 1:50 The antigen is glutaraldehyde (0.05%) and paraformaldehyde (1%) resistant. Researchers should empirically determine the suitability of the Ly6c1 ly6c1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lymphocyte antigen 6C2, MACROPHAGE PRECURSOR CELLS, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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