Rat anti-Mouse Ly-6A/E Monoclonal Antibody | anti-Ly-6A/E antibody
RAT ANTI MOUSE Ly-6A/E
Gene Names
Ly6a; TAP; Sca1; Sca-1; Ly-6A.2; Ly-6A/E; Ly-6E.1
Reactivity
Mouse
Applications
Immunohistochemistry, Flow Cytometry, Immunoprecipitation, Western Blot
Synonyms
Ly-6A/E; Monoclonal Antibody; RAT ANTI MOUSE Ly-6A/E; anti-Ly-6A/E antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
D7
Specificity
Ly-6A/E
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
0.5 mg/mL (varies by lot)
Sequence Length
134
Applicable Applications for anti-Ly-6A/E antibody
Immunohistology-Frozen, Flow cytometry (FC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Where this antibody has not been tested for use in a particular technique this does not
necessarily exclude its use in such procedures. Suggested working dilutions are given as
a guide only. It is recommended that the user titrates the antibody for use in their own
system using appropriate negative/positive controls.
Perservative Stabilisers
<0.1% Sodium Azide
Preparation
Purified IgG prepared from ascites or tissue culture supernatant
Immunogen
IL-2-dependent mouse T cell line CTL-L.
Buffer Solution
Borate buffered saline
Target Species
Mouse
Preparation and Storage
This product is shipped at ambient temperature. It is recommended to aliquot and store at
-20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for
short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in
frost-free freezers is not recommended.
Related Product Information for anti-Ly-6A/E antibody
Rat anti Mouse Ly-6A/E antibody, clone D7 recognises members of the lymphocyte activation protein-6 (Ly-6) multigene family. Specifically, it recognises Ly-6A.2 and Ly-6E.1. Ly-6A/E is also known as stem cell antigen-1 (Sca-1). It is an 18kDa mouse glycosyl phosphatidylinositol-anchored cell surface protein of the Ly-6 gene family. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly-6.1 and Ly-6.2 allotypes. As such, it is the most common marker used for enriching adult hematopoietic stem cells. It has varied functions, it plays a role in bone formation, myoblast proliferation and differentiation and the activation and immunosuppressive function of T cells. Rat anti Mouse Ly-6A/E antibody, clone D7 has been reported to induce T cell activation. Removal of Sodium Azide is recommended prior to use in functional assays.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
lymphocyte antigen 6A-2/6E-1
NCBI Official Synonym Full Names
lymphocyte antigen 6 complex, locus A
NCBI Official Symbol
Ly6a
NCBI Official Synonym Symbols
TAP; Sca1; Sca-1; Ly-6A.2; Ly-6A/E; Ly-6E.1
NCBI Protein Information
lymphocyte antigen 6A-2/6E-1; T-cell-activating protein; stem cell antigen 1
UniProt Protein Name
Lymphocyte antigen 6A-2/6E-1
UniProt Gene Name
Ly6a
UniProt Synonym Gene Names
Ly6; Ly-6A.2/Ly-6E.1; SCA-1; TAP
UniProt Entry Name
LY6A_MOUSE
Uniprot Description
Ly6A: T-cell activation.
Protein type: Cell surface
Cellular Component: membrane; plasma membrane; intracellular; external side of plasma membrane
Research Articles on Ly-6A/E
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Product Notes
The Ly-6A/E ly6a (Catalog #AAA214527) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The RAT ANTI MOUSE Ly-6A/E reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Ly-6A/E can be used in a range of immunoassay formats including, but not limited to, Immunohistology-Frozen, Flow cytometry (FC), Immunoprecipitation (IP), Western Blot (WB). Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls. Researchers should empirically determine the suitability of the Ly-6A/E ly6a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ly-6A/E, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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