Testing Data
(Whole blood monocytes were stained with either A) MBS6013492 or B) PE-conjugated isotype control and PerCP-conjugated human CD14.)
Mouse anti-Human LILRA5 Monoclonal Antibody | anti-LILRA5 antibody
LILRA5 (Leukocyte Immunoglobulin-like Receptor Subfamily A Member 5, CD85 Antigen-like Family Member F, Immunoglobulin-like Transcript 11, ILT-11, Leukocyte Immunoglobulin-like Receptor 9, LIR-9, CD85f, ILT11, LILRB7, LIR9) (PE)
Gene Names
LILRA5; CD85; LIR9; CD85F; ILT11; LIR-9; ILT-11; LILRB7
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
LILRA5; Monoclonal Antibody; LILRA5 (Leukocyte Immunoglobulin-like Receptor Subfamily A Member 5; CD85 Antigen-like Family Member F; Immunoglobulin-like Transcript 11; ILT-11; Leukocyte Immunoglobulin-like Receptor 9; LIR-9; CD85f; ILT11; LILRB7; LIR9) (PE); Anti -LILRA5 (Leukocyte Immunoglobulin-like Receptor Subfamily A Member 5; anti-LILRA5 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2A
Clone Number
12K126
Specificity
Recognizes human LILRA5.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-LILRA5 antibody
Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in Flow Cytometry.
Immunogen
Recombinant corresponding to human LILRA5 expressed in CHO cell line.
Emission
565-605nm
Excitation
488nm
Preparation and Storage
May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months at 4 degree C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Testing Data
(Whole blood monocytes were stained with either A) MBS6013492 or B) PE-conjugated isotype control and PerCP-conjugated human CD14.)
Testing Data
(Whole blood monocytes were stained with either A) MBS6013492 or B) PE-conjugated isotype control and PerCP-conjugated human CD14.)
Related Product Information for anti-LILRA5 antibody
ILT11 is a 39-40kD Group 2 member of the LILR family of innate immune receptors. It is expressed on monocytes and perhaps neutrophils, and its activation results in the secretion of pro-inflammatory cytokines, such as TNF-A and IL-1B. Mature human ILT11 is a 258aa type I transmembrane glycoprotein. It has a 227aa extracellular domain aa42-268 that contains two C2 type Ig-like domains aa51-136 and 142-230, and a 10aa cytoplasmic tail. ILT11 has three potential splice forms. One is a 35kD soluble form of the molecule described above that shows a 27aa substitution for aa239-299. The other two splice forms are analogous to the above membrane and soluble forms, but demonstrate signal sequence cleavage further downstream after Ala51. Over aa41-268, human ILT11 shares 58%aa identity with mouse LIR-9.
Product Categories/Family for anti-LILRA5 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,755 Da
NCBI Official Full Name
leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 2
NCBI Official Synonym Full Names
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
NCBI Official Symbol
LILRA5
NCBI Official Synonym Symbols
CD85; LIR9; CD85F; ILT11; LIR-9; ILT-11; LILRB7
NCBI Protein Information
leukocyte immunoglobulin-like receptor subfamily A member 5; leukocyte Ig-like receptor 9; CD85 antigen-like family member F; leukocyte immunoglobulin-like receptor 9; immunoglobulin-like transcript 11 protein; leukocyte immunoglobulin-like receptor subfamily A member 5 soluble; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 7
UniProt Protein Name
Leukocyte immunoglobulin-like receptor subfamily A member 5
Protein Family
UniProt Gene Name
LILRA5
UniProt Synonym Gene Names
ILT11; LILRB7; LIR9; ILT-11; LIR-9
UniProt Entry Name
LIRA5_HUMAN
NCBI Description
The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
LILRA5: May play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC antigen recognition. 4 isoforms of the human protein are produced by alternative splicing
Chromosomal Location of Human Ortholog: 19q13.4
Cellular Component: integral to membrane
Biological Process: innate immune response
Research Articles on LILRA5
Similar Products
Product Notes
The LILRA5 lilra5 (Catalog #AAA6013492) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The LILRA5 (Leukocyte Immunoglobulin-like Receptor Subfamily A Member 5, CD85 Antigen-like Family Member F, Immunoglobulin-like Transcript 11, ILT-11, Leukocyte Immunoglobulin-like Receptor 9, LIR-9, CD85f, ILT11, LILRB7, LIR9) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LILRA5 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Suitable for use in Flow Cytometry. Researchers should empirically determine the suitability of the LILRA5 lilra5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LILRA5, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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