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SDS-PAGE

LILRA5 recombinant protein

Human LILRA5 Protein (Fc Tag)

Gene Names
LILRA5; CD85; LIR9; CD85F; ILT11; LIR-9; ILT-11; LILRB7
Purity
> 95 % as determined by SDS-PAGE.
Synonyms
LILRA5; Human LILRA5 Protein (Fc Tag); ILT11; LILRB7; LIR9; LILRA5 recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE.
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
299
Application Notes
The recombinant human LILRA5 consists 465 amino acids and predicts a molecular mass of 52 kDa.
Predicted N Terminal
Gly 42
Endotoxin
<1.0 EU per mug protein as determined by the LAL method.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for LILRA5 recombinant protein
Background: LILRA5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LILR are a family of receptors possessing extracellular immunoglobulin domains. They are also known as CD85, ILTs and LIR, and can exert immunomodulatory effects on a wide range of immune cells. ILT-11 contains 2 Ig-like C2-type (immunoglobulin-like) domains. It can be detected n tissues of the hematopoietic system, including bone marrow, spleen, lymph node and peripheral leukocytes. Crosslink of ILT-11 on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses.

Description: A DNA sequence encoding the human LILRA5 (NP_067073.1) (Met1-Arg268) was expressed with the Fc region of human IgG1 at the C-terminus.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,852 Da
NCBI Official Full Name
leukocyte immunoglobulin-like receptor subfamily A member 5 isoform 1
NCBI Official Synonym Full Names
leukocyte immunoglobulin like receptor A5
NCBI Official Symbol
LILRA5
NCBI Official Synonym Symbols
CD85; LIR9; CD85F; ILT11; LIR-9; ILT-11; LILRB7
NCBI Protein Information
leukocyte immunoglobulin-like receptor subfamily A member 5
UniProt Protein Name
Leukocyte immunoglobulin-like receptor subfamily A member 5
UniProt Gene Name
LILRA5
UniProt Synonym Gene Names
ILT11; LILRB7; LIR9; ILT-11; LIR-9

NCBI Description

The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

LILRA5: May play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC antigen recognition. 4 isoforms of the human protein are produced by alternative splicing

Chromosomal Location of Human Ortholog: 19q13.42

Research Articles on LILRA5

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Product Notes

The LILRA5 lilra5 (Catalog #AAA2545200) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant human LILRA5 consists 465 amino acids and predicts a molecular mass of 52 kDa. Researchers should empirically determine the suitability of the LILRA5 lilra5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LILRA5, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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