Western Blot (WB)
(Western Blot analysis of K-562 cells using SLP76 Monoclonal Antibody at dilution of 1:10000.)
Mouse anti-Human LCP2 Monoclonal Antibody | anti-LCP2 antibody
LCP2 Monoclonal Antibody
Gene Names
LCP2; SLP76; SLP-76
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Protein A purification
Synonyms
LCP2; Monoclonal Antibody; LCP2 Monoclonal Antibody; 76 kDa tyrosine phosphoprotein; CG8697; LCP 2; Lymphocyte cytosolic protein 2; SH2 domain containing leukocyte protein 76 KD; SH2 domain containing leukocyte protein of 76kD; SH2 domain containing leukocyte protein of 76kDa; SH2 domain-containing leukocyte protein of 76 kDa; SLP 76; SLP 76 tyrosine phosphoprotein; SLP-76; SLP-76 tyrosine phosphoprotein; SLP76; SLP76 tyrosine phosphoprotein; anti-LCP2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4H10B1
Purity/Purification
Protein A purification
Concentration
1mg/mL (varies by lot)
Sequence Length
533
Applicable Applications for anti-LCP2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:5000-1:20000
Immunogen
Fusion protein of SLP76
Buffer
PBS with 0.1% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Western Blot (WB)
(Western Blot analysis of K-562 cells using SLP76 Monoclonal Antibody at dilution of 1:10000.)
Western Blot (WB)
(Western Blot analysis of K-562 cells using SLP76 Monoclonal Antibody at dilution of 1:10000.)
Related Product Information for anti-LCP2 antibody
LCP2, also named as SLP76, is an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. It contains an N-terminal leucine Zip motif, a tyrosine-rich domain, a proline-rich domain and a C-terminal SH2 domain. It is constitutively associated with the growth factor receptor-bound protein 2 (Grb2)-related adapter protein 2 (Grap2, a.k.a. GADS) through the interaction of its proline residues with one of the SH3 domains of Grap2. SLP76 associates with growth factor receptor bound protein 2 (Grap2), and is thought to play a role TCR-mediated intracellular signal transduction. SLP76 is also expressed by mast cells, and mast cell activation was markedly impaired in SLP76-deficient mice.
Product Categories/Family for anti-LCP2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated: 60kDa
Observed: 76kDa
Observed: 76kDa
NCBI Official Full Name
lymphocyte cytosolic protein 2
NCBI Official Synonym Full Names
lymphocyte cytosolic protein 2
NCBI Official Symbol
LCP2
NCBI Official Synonym Symbols
SLP76; SLP-76
NCBI Protein Information
lymphocyte cytosolic protein 2
UniProt Protein Name
Lymphocyte cytosolic protein 2
Protein Family
UniProt Gene Name
LCP2
UniProt Synonym Gene Names
SLP76
NCBI Description
This gene encodes an adapter protein that acts as a substrate of the T cell antigen receptor (TCR)-activated protein tyrosine kinase pathway. The encoded protein associates with growth factor receptor bound protein 2, and is thought to play a role TCR-mediated intracellular signal transduction. A similar protein in mouse plays a role in normal T-cell development and activation. Mice lacking this gene show subcutaneous and intraperitoneal fetal hemorrhaging, dysfunctional platelets and impaired viability. [provided by RefSeq, Nov 2016]
Uniprot Description
Involved in T-cell antigen receptor mediated signaling.
Research Articles on LCP2
Similar Products
Product Notes
The LCP2 lcp2 (Catalog #AAA2549139) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The LCP2 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LCP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:5000-1:20000. Researchers should empirically determine the suitability of the LCP2 lcp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LCP2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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