Immunocytochemistry (ICC)
(Immunocytochemistry analysis of CHO K1 cells incubated with LAMP1, mAb (Ly1C6) at 1:100 and goat anti-mouse Alexa 488 secondary antibody (Image provided by Dr. Guy Groblewski, University of Wisconsin-Madison).)
Mouse LAMP1 Monoclonal Antibody | anti-Lysosomal-associated membrane protein 1 antibody
LAMP1 monoclonal antibody (Ly1C6)
Gene Names
Lamp1; LGP120
Reactivity
Human, Rat, Hamster
Applications
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Purity
Protein G affinity purified.
Synonyms
LAMP1; Monoclonal Antibody; LAMP1 monoclonal antibody (Ly1C6); anti-Lysosomal-associated membrane protein 1 antibody
Host
Mouse
Reactivity
Human, Rat, Hamster
Clonality
Monoclonal
Isotype
IgG1
Clone Number
LY1C6
Specificity
Recognizes human, rat and hamster LAMP1. Detects a band of ~120kDa by Western blot.
Purity/Purification
Protein G affinity purified.
Form/Format
Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Sequence Length
407
Applicable Applications for anti-Lysosomal-associated membrane protein 1 antibody
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Electron Microscopy (EM)
Application Notes
Immunocytochemistry (1:100)
Suggested dilutions/conditions may not be available for all applications.
Detects a band of ~120kDa by Western blot.
Suggested dilutions/conditions may not be available for all applications.
Detects a band of ~120kDa by Western blot.
Immunogen
Rat liver lysosomal membrane preparation.
Preparation and Storage
Long term storage: -20 degree C
Avoid freeze/thaw cycles.
Avoid freeze/thaw cycles.
Immunocytochemistry (ICC)
(Immunocytochemistry analysis of CHO K1 cells incubated with LAMP1, mAb (Ly1C6) at 1:100 and goat anti-mouse Alexa 488 secondary antibody (Image provided by Dr. Guy Groblewski, University of Wisconsin-Madison).)
Immunocytochemistry (ICC)
(Immunocytochemistry analysis of CHO K1 cells incubated with LAMP1, mAb (Ly1C6) at 1:100 and goat anti-mouse Alexa 488 secondary antibody (Image provided by Dr. Guy Groblewski, University of Wisconsin-Madison).)
Related Product Information for anti-Lysosomal-associated membrane protein 1 antibody
Lysosome-associated membrane proteins (LAMP1 and LAMP2) are type I integral membrane protein that are transported from the trans-Golgi network to endosomes and then lysosomes. Following activation of platelets, T-cells, neutrophils, or endothelium, LAMP1 and LAMP2 are expressed on the cell surface. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, and loss of LAMP2 expression is associated with impaired autophagy observed in Danons disease.
Product Categories/Family for anti-Lysosomal-associated membrane protein 1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
43,969 Da
NCBI Official Full Name
Lysosome-associated membrane glycoprotein 1
NCBI Official Synonym Full Names
lysosomal-associated membrane protein 1
NCBI Official Symbol
Lamp1
NCBI Official Synonym Symbols
LGP120
NCBI Protein Information
lysosome-associated membrane glycoprotein 1
UniProt Protein Name
Lysosome-associated membrane glycoprotein 1
UniProt Gene Name
Lamp1
UniProt Synonym Gene Names
Lamp-1; LAMP-1; Lysosome-associated membrane protein 1; LGP-120
UniProt Entry Name
LAMP1_RAT
NCBI Description
a lysosomal acidic membrane protein [RGD, Feb 2006]
Uniprot Description
LAMP1: Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Belongs to the LAMP family.
Protein type: Membrane protein, integral
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Product Notes
The Lysosomal-associated membrane protein 1 lamp1 (Catalog #AAA565007) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The LAMP1 monoclonal antibody (Ly1C6) reacts with Human, Rat, Hamster and may cross-react with other species as described in the data sheet. AAA Biotech's LAMP1 can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Electron Microscopy (EM). Immunocytochemistry (1:100) Suggested dilutions/conditions may not be available for all applications. Detects a band of ~120kDa by Western blot. Researchers should empirically determine the suitability of the Lysosomal-associated membrane protein 1 lamp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAMP1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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