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Immunohistochemistry (IHC)

Mouse Lamin A+C Monoclonal Antibody

Mouse Anti-Lamin A+C [JOL2]

Reactivity
Human, African Green Monkey
Applications
Immunoprecipitation, Western Blot, Immunohistochemistry
Purity
Protein G
Synonyms
Lamin A+C; Monoclonal Antibody; Mouse Anti-Lamin A+C [JOL2]; 70 kDa Lamin antibody; Cardiomyopathy dilated 1A (autosomal dominant) antibody; CDCD1 antibody; CDDCantibody; Charcot Marie Tooth Disease Axonal Type 2B1 antibody; CMD1A antibody; CMT2B1 antibody; EMD2antibody; FPL antibody; FPLD antibody; HGPS antibody; IDC antibody; Lamin A/C antibody; Lamin A/C Isoform 1Precursor antibody; Lamin A/C Isoform 2 antibody; Lamin A/C Isoform 3 antibody; LDP1 antibody; LFPantibody; LGMD1B antibody; Limb girdle muscular dystrophy 1B (autosomal dominant) antibody; LMN 1 antibody; LMN Aantibody; LMN C antibody; LMN1 antibody; LMNA antibody; LMNC antibody; NY REN 32 antigen antibody; PRO1antibody; Progeria 1 (Hutchinson Gilford Type) antibody; Renal carcinoma antigen NY REN 32 antibody; Renalcarcinoma antigen NYREN32 antibody; anti-Lamin A+C antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, African Green Monkey
Clonality
Monoclonal
Isotype
IgG1
Clone Number
JOL2
Specificity
The antibody reacts with both recombinant and native lamin A and C. It has been shown to bind to an epitope between amino acids 464-572
Purity/Purification
Protein G
Form/Format
Purified antibody (from supernatant) containing PBS + 0.09% sodium azide
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-Lamin A+C antibody
Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes
Optimal antibody dilution should be determined by titration, however as a guideline try at: IHC (P): 4ug/ml
Target Antigen
Lamin A+C
Immunogen
Recombinant human lamin A
Myeloma/fusion Partners
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2-0/Ag4 myeloma cell line

Immunohistochemistry (IHC)

Immunohistochemistry (IHC)
References
Vaughan, A. et al. (2001) Both emerin and lamin C depend on lamin A for localization at the nuclear envelope. CellSci. 114 (pt 14): 2577 - 2590.PMID: 11683386

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Product Notes

The Lamin A+C (Catalog #AAA375414) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Lamin A+C [JOL2] reacts with Human, African Green Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's Lamin A+C can be used in a range of immunoassay formats including, but not limited to, Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Optimal antibody dilution should be determined by titration, however as a guideline try at: IHC (P): 4ug/ml. Researchers should empirically determine the suitability of the Lamin A+C for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lamin A+C, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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