Western Blot (WB)
(Western Blot of rat brain tissue lysate was probed with MBS633532 (0.5ug/ml). Proteins were visualized using a IgG (HRP) goat anti-rat secondary antibody and chemiluminescence detection system. Arrow indicates Kv1.2 (~65kD).)
Mouse anti-Rat Kv1.2 Monoclonal Antibody | anti-Kv1.2 antibody
Kv1.2 (Kcna2, Voltage-gated Potassium Channel) (APC)
Western Blot (WB)
(Western Blot of rat brain tissue lysate was probed with MBS633532 (0.5ug/ml). Proteins were visualized using a IgG (HRP) goat anti-rat secondary antibody and chemiluminescence detection system. Arrow indicates Kv1.2 (~65kD).)
Western Blot (WB)
(Western Blot of rat brain tissue lysate was probed with MBS633532 (0.5ug/ml). Proteins were visualized using a IgG (HRP) goat anti-rat secondary antibody and chemiluminescence detection system. Arrow indicates Kv1.2 (~65kD).)
Immunostaining (IS)
(Paraffin-embedded rat cerebellum tissue was prepared using heat-induced epitope retrieval in citrate buffer, pH 6.0. Immunostaining was performed using a 1:500 dilution ofMBS633532. Staining pattern appears to be restricted to basket cells above Purkinje cells (granular layer junction))
Immunostaining (IS)
(Paraffin-embedded rat cerebellum tissue was prepared using heat-induced epitope retrieval in citrate buffer, pH 6.0. Immunostaining was performed using a 1:500 dilution ofMBS633532. Staining pattern appears to be restricted to basket cells above Purkinje cells (granular layer junction))
Immunostaining (IS)
(Paraffin-embedded rat cerebellum tissue was prepared using heat-induced epitope retrieval in citrate buffer, pH 6.0. Immunostaining was performed using a 1:500 dilution ofMBS633532. The staining pattern appears to be restricted to the hippocampal area.)
Immunostaining (IS)
(Paraffin-embedded rat cerebellum tissue was prepared using heat-induced epitope retrieval in citrate buffer, pH 6.0. Immunostaining was performed using a 1:500 dilution ofMBS633532. The staining pattern appears to be restricted to the hippocampal area.)
NCBI and Uniprot Product Information
NCBI Description
delayed-rectifier K+ channel expressed in heart and brain [RGD, Feb 2006]
Uniprot Description
Kv1.2: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Channel, potassium; Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: presynaptic membrane; endoplasmic reticulum membrane; voltage-gated potassium channel complex; lamellipodium; integral to plasma membrane; axon; dendrite; integral to membrane; perikaryon; nerve terminal; cell junction; endosome
Molecular Function: protein binding; voltage-gated potassium channel activity; delayed rectifier potassium channel activity; outward rectifier potassium channel activity
Biological Process: optic nerve structural organization; generation of action potential; regulation of circadian sleep/wake cycle, non-REM sleep; sensory perception of pain; regulation of dopamine secretion; protein oligomerization; protein homooligomerization
Research Articles on Kv1.2
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Product Notes
The Kv1.2 kcna2 (Catalog #AAA6242506) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Kv1.2 (Kcna2, Voltage-gated Potassium Channel) (APC) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Kv1.2 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the Kv1.2 kcna2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kv1.2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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