Testing Data
(Immunocytochemistry of HeLa cells using anti- KDM5C (C-terminus) antibody diluted 1:150)
Mouse anti-Human KDM5C Monoclonal Antibody | anti-KDM5C antibody
KDM5C Antibody
Reactivity
Human
Purity
Affinity purified
Synonyms
KDM5C; Monoclonal Antibody; KDM5C Antibody; MRXJ; SMCX; MRXSJ; XE169; MRXSCJ; JARID1C; DXS1272E; anti-KDM5C antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Specificity
This antibody detects endogenous levels of KDM5C and does not corss-react with related proteins
Purity/Purification
Affinity purified
Form/Format
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%, glycerol
Immunogen
Purified recombinant human KDM5C (C-terminus) protein fragments expressed in E Coli
Cellular Localization
Nucleus
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles
Testing Data
(Immunocytochemistry of HeLa cells using anti- KDM5C (C-terminus) antibody diluted 1:150)
Testing Data
(Immunocytochemistry of HeLa cells using anti- KDM5C (C-terminus) antibody diluted 1:150)
Testing Data #2
(Western blot detection of KDM5C(C-terminus) antibody in Hela&293 cell lysates using KDM5C(C-terminus) antibody (1:1000 diluted). Predicted band size: 176KDa Observed band size: 220KDa)
Testing Data #2
(Western blot detection of KDM5C(C-terminus) antibody in Hela&293 cell lysates using KDM5C(C-terminus) antibody (1:1000 diluted). Predicted band size: 176KDa Observed band size: 220KDa)
Related Product Information for anti-KDM5C antibody
UniPort Summary Function: Histone demethylase that specifically demethylates ´Lys-4´ of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 ´Lys-9´, H3 ´Lys-27´, H3 ´Lys-36´, H3 ´Lys-79´ or H4 ´Lys-20´. Demethylates trimethylated and dimethylated but not monomethylated H3 ´Lys-4´. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements.
Entrez Summary: This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked mental retardation. Alternative splicing results in multiple transcript variants.
Entrez Summary: This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked mental retardation. Alternative splicing results in multiple transcript variants.
Product Categories/Family for anti-KDM5C antibody
NCBI and Uniprot Product Information
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
220kDa
Protein Family
Similar Products
Product Notes
The KDM5C (Catalog #AAA857783) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The KDM5C Antibody reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "KDM5C, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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