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Mouse IL-6 Monoclonal Antibody | anti-IL6 antibody

MOUSE ANTI SHEEP INTERLEUKIN-6

Reactivity
Reacts with: Monkey
N.B. Antibody reactivity and working conditions may vary between species.
Applications
ELISA, Flow Cytometry, Functional Assay, Western Blot
Synonyms
IL-6; Monoclonal Antibody; MOUSE ANTI SHEEP INTERLEUKIN-6; anti-IL6 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Reacts with: Monkey
N.B. Antibody reactivity and working conditions may vary between species.
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4B6
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Sequence Length
208
Applicable Applications for anti-IL6 antibody
ELISA (EIA), Flow cytometry (FC/FACS)*, Western Blot (WB)
Application Notes
Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
ELISA: Maximum Dilution: 5ug/ml (as a coating antibody)
Flow Cytometry: Application Note: Membrane permeabilization is required for this application. MyBioSource recommend the use of Leucoperm for this purpose.
Perservative Stabilisers
0.1% Sodium Azide
Buffer Solution
Phosphate buffered saline
Target Species
Sheep
Immunogen
Recombinant ovine IL-6
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Related Product Information for anti-IL6 antibody
Mouse anti Sheep Interleukin-6 antibody, clone 4B6 recognizes ovine interleukin-6 (IL-6) and has also been reported to recognise recombinant human IL-6 and bovine IL-6 transfected cells.Mouse anti Sheep Interleukin-6 antibody, clone 4B6 does not cross react with ovine IL-1 beta, IL-8, MCP-1 or TNF alpha.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,446 Da
NCBI Official Full Name
interleukin-6
NCBI Official Symbol
IL6
NCBI Protein Information
interleukin-6; IL-6
UniProt Protein Name
Interleukin-6
Protein Family
UniProt Gene Name
IL6
UniProt Synonym Gene Names
IL-6
UniProt Entry Name
IL6_SHEEP

Uniprot Description

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation ().

Research Articles on IL6

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Product Notes

The IL6 il6 (Catalog #AAA212254) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MOUSE ANTI SHEEP INTERLEUKIN-6 reacts with Reacts with: Monkey N.B. Antibody reactivity and working conditions may vary between species. and may cross-react with other species as described in the data sheet. AAA Biotech's IL-6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Flow cytometry (FC/FACS)*, Western Blot (WB). Flow Cytometry: Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. ELISA: Maximum Dilution: 5ug/ml (as a coating antibody) Flow Cytometry: Application Note: Membrane permeabilization is required for this application. MyBioSource recommend the use of Leucoperm for this purpose. . Researchers should empirically determine the suitability of the IL6 il6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-6, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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