Rabbit anti-Mouse IFNGR1 Monoclonal Antibody | anti-IFNGR1 antibody
Recombinant Anti-IFNGR1 Antibody, Rabbit Monoclonal
Gene Names
Ifngr1; Ifgr; CD119; Ifngr; Nktar; IFN-gammaR
Reactivity
Mouse
Applications
ELISA
Purity
Protein A
Synonyms
IFNGR1; Monoclonal Antibody; Recombinant Anti-IFNGR1 Antibody; Rabbit Monoclonal; IFNGR1/CD119 Antibody; Rabbit MAb; interferon gamma receptor 1; Anti-CD119 Antibody; Anti-Ifgr Antibody; Anti-IFN-gammaR Antibody; Anti-Ifngr Antibody; Anti-Nktar Antibody; anti-IFNGR1 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
074
Specificity
Mouse IFNGR1/CD119
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-IFNGR1 antibody
ELISA (EIA) (Det)
Application Notes
ELISA (Det): This antibody will detect Mouse IFNGR1/CD119 in ELISA pair set.
In a sandwich ELISA, it can be used as detection antibody when paired with.
In a sandwich ELISA, it can be used as detection antibody when paired with.
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Mouse IFNGR1/CD119 Protein
Conjugation
Unconjugated
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IFNGR1/CD119 (rM IFNGR1/CD119).
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-IFNGR1 antibody
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. CD119 (cluster of differentiation 119), also known as IFNGR1 (interferon-gamma receptor 1), is part of the heterodimeric gamma interferon receptor which consists of IFNGR1 (CD119) and IFNGR2. The IFNGR1 gene encodes the ligand-binding chain (alpha) of the interferon receptor while the IFNGR gene encodes the non-ligand binding partner. The ability of the interferon-gamma was achieved through binding to the interferon receptor CD119. After binding, the products of activated T-lymphocytes interferon-gamma exerts antiviral activity, growth inhibitory effect, and several immune-regulatory activities on a variety of cell types.
References
Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12Novick D, et al. (1987) The human interferon-gamma receptor. The journal of biological chemistry. 262 (18): 8483-7
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,343 Da
NCBI Official Full Name
interferon gamma receptor 1
NCBI Official Synonym Full Names
interferon gamma receptor 1
NCBI Official Symbol
Ifngr1
NCBI Official Synonym Symbols
Ifgr; CD119; Ifngr; Nktar; IFN-gammaR
NCBI Protein Information
interferon gamma receptor 1; IFN-gamma-R1; INF-g receptor; IFN-gamma receptor 1; interferon-gamma receptor 1
UniProt Protein Name
Interferon gamma receptor 1
Protein Family
UniProt Gene Name
Ifngr1
UniProt Synonym Gene Names
Ifngr; IFN-gamma receptor 1
UniProt Entry Name
INGR1_MOUSE
Uniprot Description
Function: Receptor for interferon gamma. Two receptors bind one interferon gamma dimer.
Subcellular location: Membrane; Single-pass type I membrane protein.
Post-translational modification: Phosphorylated at Ser/Thr residues.
Sequence similarities: Belongs to the type II cytokine receptor family.Contains 2 fibronectin type-III domains.Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Sequence caution: The sequence AAA37895.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
Research Articles on IFNGR1
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Product Notes
The IFNGR1 ifngr1 (Catalog #AAA8111945) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-IFNGR1 Antibody, Rabbit Monoclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IFNGR1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA) (Det). ELISA (Det): This antibody will detect Mouse IFNGR1/CD119 in ELISA pair set. In a sandwich ELISA, it can be used as detection antibody when paired with. Researchers should empirically determine the suitability of the IFNGR1 ifngr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IFNGR1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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