Mouse Hypoxia Inducible Factor 1b Monoclonal Antibody
Hypoxia Inducible Factor 1b (HIF-1b, ARNT, Aryl hydrocarbon Receptor Nuclear Translocator)
Reactivity
Bovine, Ferret, Human, Mouse, Rat, Sheep
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
Hypoxia Inducible Factor 1b; Monoclonal Antibody; Hypoxia Inducible Factor 1b (HIF-1b; ARNT; Aryl hydrocarbon Receptor Nuclear Translocator); Anti -Hypoxia Inducible Factor 1b (HIF-1b; anti-Hypoxia Inducible Factor 1b antibody
Host
Mouse
Reactivity
Bovine, Ferret, Human, Mouse, Rat, Sheep
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
3C145
Specificity
Recognizes human Hypoxia-inducible factor 1 beta (HIF-1 beta, ARNT) Species crossreactivity: Human, bovine, sheep, mouse, rat and ferret
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.
Applicable Applications for anti-Hypoxia Inducible Factor 1b antibody
Western Blot (WB)
Immunogen
Fusion protein of human HIF-1beta
Positive Control
MCF7 human nuclear extracts
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Hypoxia Inducible Factor 1b antibody
Hypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. HIF-1, a nuclear protein activating gene transcription in response to reduced cellular 02 concentration, activates the transcription of VEGF, EPO, iNOS, heme oxygenase 1 and other intracellular responses critical to hypoxia. HIF-1 is a heterodimer composed of HIF-1a and HIF-1b subunits. HIF-1a most closely resembles the Drosophila protein Sim. HIF-1b is a series of aryl hydrocarbon receptor nuclear translocator (ARNT) gene products.
Product Categories/Family for anti-Hypoxia Inducible Factor 1b antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
hypoxia-inducible factor 1b
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Product Notes
The Hypoxia Inducible Factor 1b (Catalog #AAA603549) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Hypoxia Inducible Factor 1b (HIF-1b, ARNT, Aryl hydrocarbon Receptor Nuclear Translocator) reacts with Bovine, Ferret, Human, Mouse, Rat, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's Hypoxia Inducible Factor 1b can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the Hypoxia Inducible Factor 1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hypoxia Inducible Factor 1b, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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