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Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant HOXC11 protein (Right) or empty vector (Left) detected with HOXC11 antibody)

Mouse HOXC11 Monoclonal Antibody | anti-HOXC11 antibody

HOXC11 antibody

Gene Names
HOXC11; HOX3H
Applications
Flow Cytometry, Functional Assay, Immunofluorescence, Western Blot
Purity
HOXC11 antibody was purified by affinity chromatography.
Synonyms
HOXC11; Monoclonal Antibody; HOXC11 antibody; Monoclonal HOXC11; Anti-HOXC11; Homeobox C11; MGC4906; HOX 1c1; HOX-1c1; anti-HOXC11 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
4B8
Purity/Purification
HOXC11 antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
500 ug-1 mg/ml (varies by lot)
Sequence Length
304
Applicable Applications for anti-HOXC11 antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB)
Application Notes
FC: 1:100
IF: 1:100
WB: 1:2000
Biological Significance
HOXC11 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestin al development.
Cross-Reactivity
Human
Immunogen
HOXC11 antibody was raised in mouse using a full length recombinant protein of human HOXC11 (NP_055027) produced in E Coli as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Western Blot (WB)

(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant HOXC11 protein (Right) or empty vector (Left) detected with HOXC11 antibody)

Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant HOXC11 protein (Right) or empty vector (Left) detected with HOXC11 antibody)

Immunofluorescence (IF)

(Immunofluorescent staining of COS7 cells transiently transfected with recombinant HOXC11 protein using HOXC11 antibody)

Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant HOXC11 protein using HOXC11 antibody)
Related Product Information for anti-HOXC11 antibody
Mouse monoclonal HOXC11 antibody
Product Categories/Family for anti-HOXC11 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33,748 Da
NCBI Official Full Name
homeobox protein Hox-C11
NCBI Official Synonym Full Names
homeobox C11
NCBI Official Symbol
HOXC11
NCBI Official Synonym Symbols
HOX3H
NCBI Protein Information
homeobox protein Hox-C11
UniProt Protein Name
Homeobox protein Hox-C11
Protein Family
UniProt Gene Name
HOXC11
UniProt Synonym Gene Names
HOX3H
UniProt Entry Name
HXC11_HUMAN

NCBI Description

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

HOXC11: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to a promoter element of the lactase-phlorizin hydrolase gene. Belongs to the Abd-B homeobox family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: nucleoplasm; cytoplasm

Biological Process: anterior/posterior pattern formation; transcription, DNA-dependent; induction of an organ; positive regulation of transcription from RNA polymerase II promoter; embryonic digit morphogenesis; metanephros development; proximal/distal pattern formation; endoderm development

Research Articles on HOXC11

Similar Products

Product Notes

The HOXC11 hoxc11 (Catalog #AAA533406) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's HOXC11 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB). FC: 1:100 IF: 1:100 WB: 1:2000. Researchers should empirically determine the suitability of the HOXC11 hoxc11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HOXC11, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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