Mouse Hox C11 Monoclonal Antibody | anti-HOXC11 antibody

Hox C11 (Homeobox C11)

Cat. Num. AAA603368

• Gene Names: HOXC11; HOX3H; MGC4906
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: Hox C11; Monoclonal Antibody; Hox C11 (Homeobox C11); Anti -Hox C11 (Homeobox C11); anti-HOXC11 antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 8C194
• Specificity: Recognizes human Hox C11.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.

• Applicable Applications for anti-HOXC11 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blotting.; Dilution: Western Blotting: 1:1000-1:2000
• Immunogen: Partial sequence of recombinant full-length protein to human Hox C11
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Testing Data

Product Categories/Family for anti-HOXC11 antibody

Antibodies; Abs to Homeobox (HOX)

NCBI and Uniprot Product Information

• NCBI GI #: 7657166
• NCBI GeneID: 3227
• NCBI Accession #: NP_055027.1
• NCBI GenBank Nucleotide #: NM_014212.3
• UniProt Accession #: O43248; Q96DH2; A8K7D1
• Molecular Weight: 33,748 Da
• NCBI Official Full Name: homeobox protein Hox-C11
• NCBI Official Synonym Full Names: homeobox C11
• NCBI Official Symbol: HOXC11
• NCBI Official Synonym Symbols: HOX3H; MGC4906
• NCBI Protein Information: homeobox protein Hox-C11; homeo box C11; OTTHUMP00000217351; homeobox protein Hox-3H
• UniProt Protein Name: Homeobox protein Hox-C11
• Protein Family: Homeobox protein
• UniProt Gene Name: HOXC11
• UniProt Synonym Gene Names: HOX3H
• UniProt Entry Name: HXC11_HUMAN

NCBI Description

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined. [provided by RefSeq]

Uniprot Description

HOXC11: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to a promoter element of the lactase-phlorizin hydrolase gene. Belongs to the Abd-B homeobox family.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: nucleoplasm; cytoplasm

Biological Process: anterior/posterior pattern formation; transcription, DNA-dependent; induction of an organ; positive regulation of transcription from RNA polymerase II promoter; embryonic digit morphogenesis; metanephros development; proximal/distal pattern formation; endoderm development