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Testing Data

Mouse anti-Human HNRPLL Monoclonal Antibody | anti-HNRPLL antibody

HNRPLL (Heterogeneous Nuclear Ribonucleoprotein L-like, BLOCK24, Stromal RNA Regulating Factor, SRRF)

Gene Names
HNRPLL; SRRF; hnRNPLL
Reactivity
Human
Applications
Western Blot
Purity
Affinity Purified
Purified by Protein G affinity chromatography.
Synonyms
HNRPLL; Monoclonal Antibody; HNRPLL (Heterogeneous Nuclear Ribonucleoprotein L-like; BLOCK24; Stromal RNA Regulating Factor; SRRF); Anti -HNRPLL (Heterogeneous Nuclear Ribonucleoprotein L-like; anti-HNRPLL antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
9j54
Specificity
Recognizes human HNRPLL.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.4, 1% BSA and 0.05% sodium azide.
Applicable Applications for anti-HNRPLL antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Synthetic peptide corresponding to the N-terminal region of human HNRPLL
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Testing Data

Testing Data
Product Categories/Family for anti-HNRPLL antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
56,467 Da
NCBI Official Full Name
HNRPLL protein
NCBI Official Synonym Full Names
heterogeneous nuclear ribonucleoprotein L-like
NCBI Official Symbol
HNRPLL
NCBI Official Synonym Symbols
SRRF; hnRNPLL
NCBI Protein Information
heterogeneous nuclear ribonucleoprotein L-like; OTTHUMP00000128259; OTTHUMP00000128260; OTTHUMP00000203881; stromal RNA regulating factor; stromal RNA-regulating factor
UniProt Protein Name
Stromal RNA regulating factor
UniProt Gene Name
HNRPLL
UniProt Entry Name
Q5JB52_HUMAN

NCBI Description

HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM]

Uniprot Description

HNRPLL: RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC. Interacts with HNRNPL. Up-regulated in stimulated T-cells. Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 2p22.1

Cellular Component: membrane; nucleus; ribonucleoprotein complex

Molecular Function: mRNA binding; protein binding; nucleotide binding

Biological Process: mRNA processing; positive regulation of RNA splicing

Research Articles on HNRPLL

Similar Products

Product Notes

The HNRPLL hnrpll (Catalog #AAA606938) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The HNRPLL (Heterogeneous Nuclear Ribonucleoprotein L-like, BLOCK24, Stromal RNA Regulating Factor, SRRF) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HNRPLL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the HNRPLL hnrpll for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HNRPLL, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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