Western Blot (WB)
(Mouse Dyrk2 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the Dyrk2 antibody detected the Dyrk2 protein (arrow).)
Rabbit anti-Human, mouse Dyrk2 Polyclonal Antibody | anti-Dyrk2 antibody
Mouse Dyrk2 Antibody (C-term)
Western Blot (WB)
(Mouse Dyrk2 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the Dyrk2 antibody detected the Dyrk2 protein (arrow).)
Western Blot (WB)
(Mouse Dyrk2 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the Dyrk2 antibody detected the Dyrk2 protein (arrow).)
Immunohistochemistry (IHC)
(Mouse Dyrk2 Antibody (C-term) (MBS9206856)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Dyrk2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Mouse Dyrk2 Antibody (C-term) (MBS9206856)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Dyrk2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Kudo, L.C., et al. Cereb. Cortex 17(9):2108-2122(2007)
Blackshaw, S., et al. PLoS Biol. 2 (9), E247 (2004) :
Clark, A.G., et al. Science 302(5652):1960-1963(2003)
Geiger, J.N., et al. Blood 97(4):901-910(2001)
NCBI and Uniprot Product Information
Uniprot Description
DYRK2: a dual-specificity protein kinase of the DYRK family. Localizes in the cytoplasm. Phosphorylates the translation initiation factor eIF2B at Ser539, priming it for phosphorylation by glycogen synthase kinase-3.
Protein type: Protein kinase, dual-specificity (non-receptor); Protein kinase, CMGC; EC 2.7.12.1; Kinase, protein; CMGC group; DYRK family; Dyrk2 subfamily
Cellular Component: nucleoplasm; cytoplasm; nucleus; ribonucleoprotein complex; ubiquitin ligase complex
Molecular Function: transferase activity; protein serine/threonine kinase activity; ubiquitin binding; manganese ion binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; protein serine/threonine/tyrosine kinase activity; magnesium ion binding; kinase activity; ATP binding; protein kinase activity
Biological Process: smoothened signaling pathway; peptidyl-tyrosine phosphorylation; apoptosis; positive regulation of glycogen biosynthetic process; negative regulation of NFAT protein import into nucleus; protein amino acid phosphorylation; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; phosphorylation
Research Articles on Dyrk2
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Product Notes
The Dyrk2 dyrk2 (Catalog #AAA9206856) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 521-549. The Mouse Dyrk2 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Dyrk2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the Dyrk2 dyrk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Dyrk2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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