Mouse anti-Human HLA Class 1 Antigen A2,A28 Monoclonal Antibody | anti-HLA-A antibody

HLA Class 1 Antigen A2,A28 (FITC)

Cat. Num. AAA603036

• Gene Names: HLA-A; HLAA; FLJ26655
• Reactivity: Human
• Applications: Flow Cytometry, Functional Assay, Immunofluorescence
• Purity: Highly Purified; Purified by Ion Exchange chromatography.
• Synonyms: HLA Class 1 Antigen A2; A28; Monoclonal Antibody; A28 (FITC); Anti -HLA Class 1 Antigen A2; anti-HLA-A antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2a
• Clone Number: 8.L.125B
• Specificity: Recognizes the human HLA Class 1 Antigen A2,A28.
• Purity/Purification: Highly Purified; Purified by Ion Exchange chromatography.
• Form/Format: Supplied as a liquid in PBS, 1% BSA, 0.1% sodium azide. Labeled with fluorescein isothiocyanate (FITC).

• Applicable Applications for anti-HLA-A antibody: Flow Cytometry (FC/FACS), Immunofluorescence (IF)
• Application Notes: Suitable for use in Flow Cytometry, Cell Typing, Tissue Staining and Chimerism Studies.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.

Related Product Information for anti-HLA-A antibody

Antibodies can also be used for the detection of HLA antigens on the lymphocytes in whole blood samples and cells isolated from blood or lymphoid tissue. The HLA Class 1 conjugated monoclonal antibodies can be used for the detection of specific cell surface antigens.

Product Categories/Family for anti-HLA-A antibody

Antibodies; Abs to HLA

NCBI and Uniprot Product Information

• NCBI GI #: 13124681
• NCBI GeneID: 3105
• UniProt Accession #: O02860; O02922; O02968; O15506; O19520; O19521; A0EVJ8; A0EVJ9; A0EVK0; A0FKC6
• Molecular Weight: 21,196 Da
• NCBI Official Full Name: HLA class I histocompatibility antigen, A-68 alpha chain
• NCBI Official Synonym Full Names: major histocompatibility complex, class I, A
• NCBI Official Symbol: HLA-A
• NCBI Official Synonym Symbols: HLAA; FLJ26655
• NCBI Protein Information: HLA class I histocompatibility antigen, A-1 alpha chain; OTTHUMP00000161059; OTTHUMP00000161060; antigen presenting molecule; leukocyte antigen class I-A; MHC class I antigen HLA-A heavy chain
• UniProt Protein Name: MHC class I antigen
• Protein Family: HLA class I histocompatibility antigen
• UniProt Gene Name: HLA-A
• UniProt Entry Name: O02860_HUMAN

NCBI Description

HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq]

Uniprot Description

Sequence similarities: Belongs to the MHC class I family. RuleBase RU004439