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Immunohistochemistry (IHC) (Anti-FFAR3 / GPR41 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit FFAR3 / GPR41 Polyclonal Antibody | anti-FFAR3 antibody

Rabbit Polyclonal to Human FFAR3 / GPR41

Gene Names
FFAR3; FFA3R; GPR41
Reactivity
Gibbon, Gorilla, Human
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
FFAR3 / GPR41; Polyclonal Antibody; Rabbit Polyclonal to Human FFAR3 / GPR41; Anti-FFAR3 / GPR41 Antibody (Internal) IHC-plus; FFAR3; G-protein coupled receptor 41; FFA3R; Gpcr41; Gpr42; Free fatty acid receptor 3; G protein-coupled receptor 41; GPR41; Human FFAR3; anti-FFAR3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gibbon, Gorilla, Human
Clonality
Polyclonal
Specificity
Human FFAR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
346
Applicable Applications for anti-FFAR3 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (5 ug/ml)
Usage: Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from internal region of human FFAR3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Goat (81%).
Immunogen Type
Synthetic peptide
Immunogen
FFAR3 / GPR41 antibody was raised against synthetic 16 amino acid peptide from internal region of human FFAR3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Goat (81%).
Antigen Modification
Internal
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-FFAR3 / GPR41 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-FFAR3 / GPR41 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-FFAR3 / GPR41 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-FFAR3 / GPR41 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-FFAR3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-FFAR3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-FFAR3 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-FFAR3 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Product Categories/Family for anti-FFAR3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,649 Da
NCBI Official Full Name
free fatty acid receptor 3
NCBI Official Synonym Full Names
free fatty acid receptor 3
NCBI Official Symbol
FFAR3
NCBI Official Synonym Symbols
FFA3R; GPR41
NCBI Protein Information
free fatty acid receptor 3; G protein-coupled receptor 41; G-protein coupled receptor 41
UniProt Protein Name
Free fatty acid receptor 3
Protein Family
UniProt Gene Name
FFAR3
UniProt Synonym Gene Names
GPR41
UniProt Entry Name
FFAR3_HUMAN

Uniprot Description

FFAR3: Receptor for short chain fatty acids. The activity of this receptor is coupled to the formation of inositol 1,4,5- trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation. Coupled exclusively to the pertussis toxin-sensitive G(i/o)-alpha protein. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; lipid binding

Biological Process: G-protein coupled receptor protein signaling pathway; mucosal immune response; positive regulation of cytokine production during immune response; positive regulation of acute inflammatory response to non-antigenic stimulus; G-protein signaling, adenylate cyclase inhibiting pathway; negative regulation of blood pressure; regulation of norepinephrine secretion; inflammatory response; regulation of hormone biosynthetic process; positive regulation of chemokine production

Research Articles on FFAR3

Similar Products

Product Notes

The FFAR3 ffar3 (Catalog #AAA247730) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human FFAR3 / GPR41 reacts with Gibbon, Gorilla, Human and may cross-react with other species as described in the data sheet. AAA Biotech's FFAR3 / GPR41 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (5 ug/ml) Usage: Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K. Researchers should empirically determine the suitability of the FFAR3 ffar3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FFAR3 / GPR41, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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