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Mouse anti-Human Hepatocyte Growth Factor Activator Inhibitor 1 Monoclonal Antibody | anti-SPINT1 antibody

Hepatocyte Growth Factor Activator Inhibitor 1 (HAI-1, Serine Protease Inhibitor Kunitz-Type I, SPINT1) (Biotin)

Gene Names
SPINT1; HAI; HAI1; MANSC2
Reactivity
Human
Applications
ELISA
Purity
Purified
Purified
Synonyms
Hepatocyte Growth Factor Activator Inhibitor 1; Monoclonal Antibody; Hepatocyte Growth Factor Activator Inhibitor 1 (HAI-1; Serine Protease Inhibitor Kunitz-Type I; SPINT1) (Biotin); Anti -Hepatocyte Growth Factor Activator Inhibitor 1 (HAI-1; anti-SPINT1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8H110
Specificity
Recognizes human HAI-1 ectodomain.
Purity/Purification
Purified
Purified
Form/Format
Supplied as a lyophilized powder from PBS, 50ug of bovine serum albumin (BSA) per 1ug of antibody. Labeled with Biotin. Reconstitute with 200ul 40-50% glycerol, PBS.
Applicable Applications for anti-SPINT1 antibody
ELISA (EL/EIA)
Application Notes
Suitable for use in Direct ELISA.
Dilution: Direct ELISA: 0.5-2ug/mL
Immunogen
NS0-derived rhHAI-1 ectodomain.
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-SPINT1 antibody
Hepatocyte Growth Factor (HGF) Activator Inhibitor 1 (HAI-1), also known as Serine Protease Inhibitor, Kunitz-Type I (SPINT1), is an inhibitor of HGF Activator, a protease that activates HGF in response to tissue damage.
Product Categories/Family for anti-SPINT1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
58,398 Da
NCBI Official Full Name
hepatocyte growth factor activator inhibitor 1B
NCBI Official Synonym Full Names
serine peptidase inhibitor, Kunitz type 1
NCBI Official Symbol
SPINT1
NCBI Official Synonym Symbols
HAI; HAI1; MANSC2
NCBI Protein Information
kunitz-type protease inhibitor 1; HAI-1; serine protease inhibitor, Kunitz type 1; hepatocyte growth factor activator inhibitor type 1
UniProt Protein Name
Kunitz-type protease inhibitor 1
UniProt Gene Name
SPINT1
UniProt Synonym Gene Names
HAI1; HAI-1
UniProt Entry Name
SPIT1_HUMAN

NCBI Description

The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

SPINT1: Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14). 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 15q15.1

Cellular Component: extracellular space; membrane; extracellular region

Molecular Function: serine-type endopeptidase inhibitor activity

Biological Process: extracellular matrix organization and biogenesis

Research Articles on SPINT1

Similar Products

Product Notes

The SPINT1 spint1 (Catalog #AAA603498) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Hepatocyte Growth Factor Activator Inhibitor 1 (HAI-1, Serine Protease Inhibitor Kunitz-Type I, SPINT1) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Hepatocyte Growth Factor Activator Inhibitor 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in Direct ELISA. Dilution: Direct ELISA: 0.5-2ug/mL. Researchers should empirically determine the suitability of the SPINT1 spint1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hepatocyte Growth Factor Activator Inhibitor 1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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