mouse Heat Shock Cognate Protein 70 Monoclonal Antibody | anti-hspa1l antibody
Heat Shock Cognate Protein 70 (HSC70, HSP73)
Gene Names
hspa1l; hsc70; hsc70.I; MGC52655
Reactivity
Feline, Human, Monkey, Mouse
Applications
Western Blot, Immunoprecipitation, Immunohistochemistry
Purity
AscitesAscites
Synonyms
Heat Shock Cognate Protein 70; Monoclonal Antibody; Heat Shock Cognate Protein 70 (HSC70; HSP73); Anti -Heat Shock Cognate Protein 70 (HSC70; anti-hspa1l antibody
Host
mouse
Reactivity
Feline, Human, Monkey, Mouse
Clonality
Monoclonal
Isotype
IgM
Clone Number
6D447
Specificity
Mouse
Purity/Purification
Ascites
Ascites
Ascites
Applicable Applications for anti-hspa1l antibody
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Application Notes
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry.
Dilution: Western Blot: 1:2500
Immunohistochemistry: 1:50
Dilution: Western Blot: 1:2500
Immunohistochemistry: 1:50
Immunogen
Mouse spermatogenic cell protein.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-hspa1l antibody
HSC70-interacting protein (Hip) is a cytosolic protein that exists as a homo-oligomer and participates in the regulation of the heat shock protein HSC70 in eukaryotic cells. Hip interacts with the ATPase domain of HSC70 molecules through the tetratricopeptide repeats and flanking charged a-helices of Hip. This binding reaction is dependent on HSP40 in the presence of ATP and becomes Hsp40-independent if HSC70 is preincubated with ADP. Upon binding to HsSC70, Hip stabilizes the ADP-bound state of HsSC70, a conformation that has a high affinity for unfolded substrate proteins. Hip by itself binds unfolded polypeptides, suggesting that it may possess chaperone activity. Together with HSP40, Hip may regulate the chaperone activity of HSC70 by stabilizing the chaperone- substrate complex.
Product Categories/Family for anti-hspa1l antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
heat shock 70kDa protein 1-like
NCBI Official Synonym Full Names
heat shock 70kDa protein 1-like
NCBI Official Symbol
hspa1l
NCBI Official Synonym Symbols
hsc70; hsc70.I; MGC52655
NCBI Protein Information
heat shock 70kDa protein 1-like; heat shock cognate protein 70
Protein Family
Research Articles on hspa1l
1. csp interaction with Hsc 70 molecular chaperones is vital for regulated secretion in Xenopus oocytes
Similar Products
Product Notes
The hspa1l (Catalog #AAA601811) is an Antibody produced from mouse and is intended for research purposes only. The product is available for immediate purchase. The Heat Shock Cognate Protein 70 (HSC70, HSP73) reacts with Feline, Human, Monkey, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Heat Shock Cognate Protein 70 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Dilution: Western Blot: 1:2500 Immunohistochemistry: 1:50. Researchers should empirically determine the suitability of the hspa1l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Heat Shock Cognate Protein 70, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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