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Western Blot (WB) (Western Blot: Sample: Recombinant GRIP1, Human.)

Mouse anti-Human Glutamate Receptor Interacting Protein 1 (GRIP1) Monoclonal Antibody | anti-GRIP1 antibody

Monoclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1)

Gene Names
GRIP1; GRIP; FRASRS3
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Protein A + Protein G affinity chromatography
Synonyms
Glutamate Receptor Interacting Protein 1 (GRIP1); Monoclonal Antibody; Monoclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1); anti-GRIP1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
D4
Specificity
The antibody is a mouse monoclonal antibody raised against GRIP1. It has been selected for its ability to recognize GRIP1 in immunohistochemical staining and western blotting.
Purity/Purification
Protein A + Protein G affinity chromatography
Form/Format
Liquid
Concentration
1mg/mL (varies by lot)
Sequence Length
1061
Applicable Applications for anti-GRIP1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes
Western Blot: 0.5-5ug/mL
Immunohistochemistry: 5-30ug/mL
Immunocytochemistry: 5-30ug/mL
Immunogen
Recombinant Glutamate Receptor Interacting Protein 1 (GRIP1)
Cross Reactivity
Human
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Western Blot (WB)

(Western Blot: Sample: Recombinant GRIP1, Human.)

Western Blot (WB) (Western Blot: Sample: Recombinant GRIP1, Human.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
116,371 Da
NCBI Official Full Name
glutamate receptor-interacting protein 1 isoform 2
NCBI Official Synonym Full Names
glutamate receptor interacting protein 1
NCBI Official Symbol
GRIP1
NCBI Official Synonym Symbols
GRIP; FRASRS3
NCBI Protein Information
glutamate receptor-interacting protein 1
UniProt Protein Name
Glutamate receptor-interacting protein 1
UniProt Gene Name
GRIP1
UniProt Synonym Gene Names
GRIP-1

NCBI Description

This gene encodes a member of the glutamate receptor interacting protein family. The encoded scaffold protein binds to and mediates the trafficking and membrane organization of a number of transmembrane proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, May 2010]

Uniprot Description

GRIP1: a scaffold protein for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific locations in neurons. Interacts with EphA7, EphB2, KIF5A, -B, -C, GluR2, -3, GRIPAP1, liprin A1, PPFIA4, FRAS1, and PTPRF.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 12q14.3

Cellular Component: cell junction; cytosol; dendrite; endoplasmic reticulum; membrane raft; neuron projection; plasma membrane; postsynaptic membrane; recycling endosome

Molecular Function: androgen receptor binding; beta-catenin binding; glucocorticoid receptor binding; protein binding; protein C-terminus binding; receptor signaling complex scaffold activity; transcription coactivator activity

Biological Process: androgen receptor signaling pathway; dendrite development; positive regulation of transcription, DNA-templated; protein localization

Disease: Fraser Syndrome; Fraser Syndrome 3

Research Articles on GRIP1

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Product Notes

The GRIP1 grip1 (Catalog #AAA2090642) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to Glutamate Receptor Interacting Protein 1 (GRIP1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Glutamate Receptor Interacting Protein 1 (GRIP1) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). Western Blot: 0.5-5ug/mL Immunohistochemistry: 5-30ug/mL Immunocytochemistry: 5-30ug/mL. Researchers should empirically determine the suitability of the GRIP1 grip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glutamate Receptor Interacting Protein 1 (GRIP1), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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