Mouse anti-Human Glucagon-like Peptide 2 Receptor Monoclonal Antibody | anti-GLP2R antibody
Glucagon-like Peptide 2 Receptor (GLP2R)
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Dilution: Immunocytochemistry: 10ug/ml detects GLP-2R in HeLa cells. Cells were fixed with PBS containing 10% normal donkey serum, 0.1% Triton X-100 and 1% BSA. After blocking, cells were incubated with diluted G2040-39D followed by NL557-coupled anti-mouse IgGin the dark. Between each step cells were washed with PBS, BSA.
Flow Cytometry: 25ug/ml. 10ul will label 1-2.5x10e5 cells iin 200ul total reaction volume.
NCBI and Uniprot Product Information
NCBI Description
The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq]
Uniprot Description
GLP2R: This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.
Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 2
Chromosomal Location of Human Ortholog: 17p13.3
Cellular Component: integral to membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; glucagon receptor activity
Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; positive regulation of cell proliferation
Research Articles on GLP2R
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Product Notes
The GLP2R glp2r (Catalog #AAA603395) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Glucagon-like Peptide 2 Receptor (GLP2R) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Glucagon-like Peptide 2 Receptor can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS). Suitable for use in Immunocytochemistry, Flow Cytometry and ELISA. Dilution: Immunocytochemistry: 10ug/ml detects GLP-2R in HeLa cells. Cells were fixed with PBS containing 10% normal donkey serum, 0.1% Triton X-100 and 1% BSA. After blocking, cells were incubated with diluted G2040-39D followed by NL557-coupled anti-mouse IgGin the dark. Between each step cells were washed with PBS, BSA. Flow Cytometry: 25ug/ml. 10ul will label 1-2.5x10e5 cells iin 200ul total reaction volume. Researchers should empirically determine the suitability of the GLP2R glp2r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glucagon-like Peptide 2 Receptor, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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