Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Human Calmodulin (CAM) Polyclonal Antibody | anti-CAM antibody
Polyclonal Antibody to Calmodulin (CAM)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- ADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Lung tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Lung tissue))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the EF-hand calcium-binding protein family. It is one of three genes which encode an identical calcium binding protein which is one of the four subunits of phosphorylase kinase. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
Uniprot Description
Calmodulin: a calcium-binding small regulatory protein that mediates the control of a large number of enzymes by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Has four functional calcium-binding domains. Phosphorylation and ubiquitination result in a decreased activity.
Protein type: Calcium-binding; Protein phosphatase, regulatory subunit
Chromosomal Location of Human Ortholog: 14q32.11
Cellular Component: calcium channel complex; cytoplasm; cytosol; extracellular region; nucleoplasm; plasma membrane; protein complex; sarcomere; spindle pole
Molecular Function: adenylate cyclase binding; calcium channel inhibitor activity; calcium ion binding; inositol trisphosphate 3-kinase activity; ion channel binding; ligand-gated ion channel activity; protein binding; protein kinase binding; protein phosphatase activator activity; protein serine/threonine kinase activator activity; Ras guanyl-nucleotide exchange factor activity; titin binding
Biological Process: detection of calcium ion; Fc-epsilon receptor signaling pathway; glycogen catabolic process; inositol phosphate metabolic process; MAPK cascade; muscle contraction; negative regulation of peptidyl-threonine phosphorylation; platelet degranulation; positive regulation of cAMP biosynthetic process; positive regulation of cyclic nucleotide metabolic process; positive regulation of cyclic-nucleotide phosphodiesterase activity; positive regulation of peptidyl-threonine phosphorylation; positive regulation of phosphoprotein phosphatase activity; positive regulation of protein amino acid autophosphorylation; positive regulation of protein dephosphorylation; positive regulation of protein serine/threonine kinase activity; protein amino acid methylation; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; regulation of heart rate; regulation of nitric-oxide synthase activity; regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; regulation of rhodopsin mediated signaling; response to calcium ion; Wnt receptor signaling pathway, calcium modulating pathway
Disease: Long Qt Syndrome 14; Ventricular Tachycardia, Catecholaminergic Polymorphic, 4
Research Articles on CAM
Similar Products
Product Notes
The CAM calm1 (Catalog #AAA2016820) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Calmodulin (CAM) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Calmodulin (CAM) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the CAM calm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- ADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE. It is sometimes possible for the material contained within the vial of "Calmodulin (CAM), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
