Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 46947(CDX4 Antibody) at dilution 1/20. (Original magnification: 200))
Rabbit anti-Human CNDP2 Polyclonal Antibody | anti-CNDP2 antibody
CNDP2 Antibody
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 46947(CDX4 Antibody) at dilution 1/20. (Original magnification: 200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 46947(CDX4 Antibody) at dilution 1/20. (Original magnification: 200))
NCBI and Uniprot Product Information
NCBI Description
CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]).[supplied by OMIM, Mar 2008]
Uniprot Description
Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly (PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase (MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation (PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells (PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis (PubMed:25964343).
Research Articles on CNDP2
Similar Products
Product Notes
The CNDP2 cndp2 (Catalog #AAA9429909) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CNDP2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CNDP2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IF: 1: 25-100. Researchers should empirically determine the suitability of the CNDP2 cndp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CNDP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
