Mouse Fibronectin, Cellular Monoclonal Antibody | anti-FN1 antibody

Fibronectin, Cellular (cFn, FN, FN1, Cold-insoluble Globulin, CIG, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, ED-B, FINC, FNZ, GFND, GFND2, LETS, MSF)

Cat. Num. AAA632161

• Gene Names: FN1; FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; DKFZp686H0342; DKFZp686I1370; DKFZp686F10164; DKFZp686O13149
• Reactivity: Chicken, Guinea Pig, Human, Rabbit, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Purified; Purified
• Synonyms: Fibronectin; Cellular; Monoclonal Antibody; Cellular (cFn; FN; FN1; Cold-insoluble Globulin; CIG; DKFZp686F10164; DKFZp686H0342; DKFZp686I1370; DKFZp686O13149; ED-B; FINC; FNZ; GFND; GFND2; LETS; MSF); Anti -Fibronectin; anti-FN1 antibody

• Host: Mouse
• Reactivity: Chicken, Guinea Pig, Human, Rabbit, Rat
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: DH1
• Specificity: Recognizes the cellular form of human Fibronectin. Specific to the extra domain A (EDA) of the molecule. Blocks chondrocyte condensation in chicken embryos.
• Purity/Purification: Purified; Purified
• Form/Format: Supplied as a liquid in PBS, 1% BSA, 0.1 % sodium azide.

• Applicable Applications for anti-FN1 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use Western Blot and Immunohistochemistry.; Dilution: Western Blot 1:100-1:2000; Immunohistochemistry 1:10-1:2000; Immunohistochemistry-Paraffin 1:10-1:2000
• Immunogen: Purified fibronectin from A8387 fibrosarcoma cells
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Related Product Information for anti-FN1 antibody

Fibronectins are diverse high molecular weight cell adhesion glycoproteins found in basement membranes, in the interstitial connective tissue matrix, and in soluble in plasma and other body fluids. In adult tissues most fibronectin is produced by hepatocytes (pFn) that differ from locally produced cellular fibronectins. cFns are found in some basement membranes during development and only in distinct tissues in adult, for instance in smooth muscle and alveolar walls of airways. cFns are abundant in the plasma of carcinoma patients and in the stroma of various carcinomas.

Product Categories/Family for anti-FN1 antibody

Antibodies; Abs to Fibronectin

NCBI and Uniprot Product Information

• NCBI GI #: 182697
• NCBI GeneID: 2335
• UniProt Accession #: O95608; O95617; P02751; Q14327; Q14328; Q53S27; Q564H7; Q59G22; Q5CZ99; Q68CX6
• Molecular Weight: 13,341 Da
• NCBI Official Full Name: fibronectin
• NCBI Official Synonym Full Names: fibronectin 1
• NCBI Official Symbol: FN1
• NCBI Official Synonym Symbols: FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; DKFZp686H0342; DKFZp686I1370; DKFZp686F10164; DKFZp686O13149
• NCBI Protein Information: fibronectin; OTTHUMP00000164053; OTTHUMP00000164054; OTTHUMP00000164055; OTTHUMP00000164056; OTTHUMP00000206760; OTTHUMP00000206762; OTTHUMP00000206763; OTTHUMP00000206765; OTTHUMP00000206766; OTTHUMP00000206767; cold-insoluble globulin; migration-stimulating factor
• UniProt Protein Name: Fibronectin
• Protein Family: Fibronectin
• UniProt Gene Name: FN1
• UniProt Entry Name: O95608_HUMAN

NCBI Description

This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. [provided by RefSeq]