Mouse FGFR1OP Monoclonal Antibody | anti-FGFR1OP antibody

FGFR1OP (FGFR1 Oncogene partner, FOP) (Biotin)

Cat. Num. AAA6173761

• Gene Names: CEP43; FOP; FGFR1OP
• Applications: Western Blot
• Purity: Purified
• Synonyms: FGFR1OP; Monoclonal Antibody; FGFR1OP (FGFR1 Oncogene partner; FOP) (Biotin); FGFR1 Oncogene partner; FOP; anti-FGFR1OP antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1,k
• Clone Number: 100000000
• Specificity: Recognizes FGFR1OP.
• Purity/Purification: Purified
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
• Sequence Length: 379

• Applicable Applications for anti-FGFR1OP antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: FGFR1OP (AAH11902, 1aa-379aa) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD.
• Conjugate: Biotin
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Testing Data

(Detection limit for recombinant GST tagged FGFR1OP is 0.3 ng/ml as a capture antibody.)

Western Blot (WB)

(Western Blot analysis of FGFR1OP expression in transfected 293T cell line by FGFR1OP monoclonal antibody (M02), clone 1E8.Lane 1: FGFR1OP transfected lysate (43.1 KDa).Lane 2: Non-transfected lysate.)

Related Product Information for anti-FGFR1OP antibody

This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq]

Product Categories/Family for anti-FGFR1OP antibody

Antibodies; Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 15080276
• NCBI GeneID: 11116
• NCBI Official Full Name: FGFR1 oncogene partner
• NCBI Official Synonym Full Names: centrosomal protein 43
• NCBI Official Symbol: CEP43
• NCBI Official Synonym Symbols: FOP; FGFR1OP
• NCBI Protein Information: FGFR1 oncogene partner
• Protein Family: FGFR1 oncogene partner

NCBI Description

This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013]