Immunohistochemistry (IHC)
(Immunochemical staining of mouse FCGR4 in mouse spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).)
Rabbit anti-Mouse FCGR4 Monoclonal Antibody | anti-FCGR4 antibody
Recombinant Anti-FCGR4 Antibody, Rabbit Monoclonal
No cross-reactivity in ELISA with Human CD16a, Human CD16b, Human CD32a, Human CD32b, Mouse FCGR3
Has cross-reactivity in ELISA with Human CD64
IHC-P: 1:100-1:500
Immunohistochemistry (IHC)
(Immunochemical staining of mouse FCGR4 in mouse spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).)
Immunohistochemistry (IHC)
(Immunochemical staining of mouse FCGR4 in mouse spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).)
Immunohistochemistry (IHC)
(Immunochemical staining of mouse FCGR4 in mouse lung with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).Positive staining was localized to pulmonary macrophage.)
Immunohistochemistry (IHC)
(Immunochemical staining of mouse FCGR4 in mouse lung with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).Positive staining was localized to pulmonary macrophage.)
Immunohistochemistry (IHC)
(Immunochemical staining of mouse FCGR4 in mouse liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining of mouse FCGR4 in mouse liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining of mouse FCGR4 in mouse intestine with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining of mouse FCGR4 in mouse intestine with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).)
NCBI and Uniprot Product Information
Uniprot Description
Receptor for the Fc region of immunoglobulin gamma (PubMed:16039578). Also acts as a receptor for the Fc region of immunoglobulin epsilon (PubMed:17558411, PubMed:18949059). Binds with intermediate affinity to both IgG2a and IgG2b (PubMed:16039578, PubMed:17558411, PubMed:19795417). Can bind to IgG2a and IgG2b monomers (PubMed:18949059). Does not display binding to IgG1 or IgG3 (PubMed:16039578). Mediates neutrophil activation by IgG complexes redundantly with Fcgr3 (PubMed:18097064). Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (PubMed:25824719). Binds with low affinity to both the a and b allotypes of IgE (PubMed:18949059). Has also been shown to bind to IgE allotype a only but not to allotype b (PubMed:17558411). Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes (PubMed:18949059). Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions (PubMed:17558411, PubMed:18949059).
Research Articles on FCGR4
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Product Notes
The FCGR4 fcgr4 (Catalog #AAA8110825) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-FCGR4 Antibody, Rabbit Monoclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FCGR4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). ELISA: 1:5000-1:10,000 IHC-P: 1:100-1:500. Researchers should empirically determine the suitability of the FCGR4 fcgr4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FCGR4, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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