Immunoassay (IA)
(The callibration curve of a sandwich assay for detection of N-terminally intact Extendin-4 using MBS838559 as the capture antibody and MBS837849 as the biotinylated detection antibody calibration curve)
Mouse anti-Human Exendin 4 Monoclonal Antibody | anti-Exendin 4 antibody
Exendin 4 antibody (biotin)
Reactivity
Human
Applications
ELISA
Purity
Exendin 4 antibody was purified from cell culture supernatant by protein A/G chromatography
Synonyms
Exendin 4; Monoclonal Antibody; Exendin 4 antibody (biotin); Monoclonal Exendin 4; Anti-Exendin 4; Exenatide; INN; Byetta; Bydureon; Exendin-4; Exendin4; anti-Exendin 4 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1 kappa
Clone Number
M81494-B
Specificity
Specific for human hemopexin
Purity/Purification
Exendin 4 antibody was purified from cell culture supernatant by protein A/G chromatography
Form/Format
Supplied in 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Sequence Length
87
Applicable Applications for anti-Exendin 4 antibody
ELISA (EIA)
Application Notes
MBS837849 can be used as the detection antibody in a matched pair immunoassay in conjunction with MBS838029 or MBS838559 as the capture antibody
Biological Significance
Exendin 4 is approved "as adjunctive therapy to improve glycemic control in patients with type 2 diabetes mellitus who are taking metformin, a biguanide, or a combination of metformin and a sulfonylurea, but have not achieved adequate glycemic control".
Cross-Reactivity
Guinea Pig
Tag/Conjugate
Biotin
Immunogen
Exendin 4 antibody was raised in Mouse using Hemopexin purified from human plasma as the immunogen
Preparation and Storage
Store at 4-8 degree C without exposure to light
Immunoassay (IA)
(The callibration curve of a sandwich assay for detection of N-terminally intact Extendin-4 using MBS838559 as the capture antibody and MBS837849 as the biotinylated detection antibody calibration curve)
Immunoassay (IA)
(The callibration curve of a sandwich assay for detection of N-terminally intact Extendin-4 using MBS838559 as the capture antibody and MBS837849 as the biotinylated detection antibody calibration curve)
Related Product Information for anti-Exendin 4 antibody
Mouse monoclonal Exendin 4 antibody (Biotin)
Product Categories/Family for anti-Exendin 4 antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
9,479 Da
NCBI Official Full Name
exendin 4
UniProt Protein Name
Exendin-4
UniProt Entry Name
EXE4_HELSU
Uniprot Description
Venom protein that mimics the incretin hormone glucagon-like peptide 1 (GLP-1). It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle.
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Product Notes
The Exendin 4 (Catalog #AAA837849) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Exendin 4 antibody (biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Exendin 4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). MBS837849 can be used as the detection antibody in a matched pair immunoassay in conjunction with MBS838029 or MBS838559 as the capture antibody. Researchers should empirically determine the suitability of the Exendin 4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Exendin 4, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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