Western Blot (WB)
(Western blot detection of ERM/Etv5 in C6, 3T3 and K562 cell lysates using ERM/Etv5 mouse mAb (1:500 diluted).Predicted band size:58KDa.Observed band size:58KDa.)
Mouse ERM/Etv5 Monoclonal Antibody | anti-ERM/Etv5 antibody
Anti-ERM/Etv5 Mouse mAb
Gene Names
ETV5; ERM
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunofluorescence
Synonyms
ERM/Etv5; Monoclonal Antibody; Anti-ERM/Etv5 Mouse mAb; ERM; Ets related protein ERM; ETS translocation variant 5; Ets variant gene 5; Ets-related protein ERM; ETV5; ETV5_HUMAN; anti-ERM/Etv5 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3H4-G3-B3
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
510
Applicable Applications for anti-ERM/Etv5 antibody
Western Blot (WB), Immunofluorescence (IF)
Immunogen
Purified recombinant fragment of human ETV5 expressed in E Coli.
Sequence Similarities
Contains 1 ETS DNA-binding domain.
Subunit Structure
Interacts (via C-terminal) with ZMYM5 (via N-terminal 120 amino acid region).
Subcellular Location
Nucleus
Western Blot (WB)
(Western blot detection of ERM/Etv5 in C6, 3T3 and K562 cell lysates using ERM/Etv5 mouse mAb (1:500 diluted).Predicted band size:58KDa.Observed band size:58KDa.)
Western Blot (WB)
(Western blot detection of ERM/Etv5 in C6, 3T3 and K562 cell lysates using ERM/Etv5 mouse mAb (1:500 diluted).Predicted band size:58KDa.Observed band size:58KDa.)
Immunocytochemistry (ICC)
(Immunocytochemistry staining of HeLa cells fixed with 1% Paraformaldehyde and using anti-ERM/Etv5 mouse mAb (dilution 1:500).)
Immunocytochemistry (ICC)
(Immunocytochemistry staining of HeLa cells fixed with 1% Paraformaldehyde and using anti-ERM/Etv5 mouse mAb (dilution 1:500).)
Related Product Information for anti-ERM/Etv5 antibody
Entrez Summary: ETS variant 5, transcription factor of the ETS family, divergent member of the winged helix-turn-helix superfamily, expressed in brain, placenta and other tissues involved in development. Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that it is required for SSC self-renewal but not differentiation, thus affected mice exhibit progressive germ cell depletion.
UniPort Summary Function: Binds to DNA sequences containing the consensus nucleotide core sequence 5-GGAA.-3.
UniPort Summary Function: Binds to DNA sequences containing the consensus nucleotide core sequence 5-GGAA.-3.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
58kDa
NCBI Official Full Name
ETS translocation variant 5
NCBI Official Synonym Full Names
ETS variant 5
NCBI Official Symbol
ETV5
NCBI Official Synonym Symbols
ERM
NCBI Protein Information
ETS translocation variant 5
UniProt Protein Name
ETS translocation variant 5
UniProt Gene Name
ETV5
UniProt Synonym Gene Names
ERM
Uniprot Description
ERM: Binds to DNA sequences containing the consensus nucleotide core sequence GGAA. Belongs to the ETS family.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 3q27.2
Cellular Component: nucleoplasm; nucleus
Molecular Function: DNA binding; protein binding; transcription factor activity
Biological Process: cell differentiation; positive regulation of transcription from RNA polymerase II promoter
Research Articles on ERM/Etv5
Similar Products
Product Notes
The ERM/Etv5 etv5 (Catalog #AAA476025) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-ERM/Etv5 Mouse mAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ERM/Etv5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). Researchers should empirically determine the suitability of the ERM/Etv5 etv5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ERM/Etv5, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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