Epithelial Cell Adhesion Molecule (Ep CAM) Monoclonal Antibody | anti-Epcam antibody
MAb to Ep CAM (aa 116-242)
NCBI and Uniprot Product Information
NCBI Description
involved in metastasis formation and tumor progression [RGD, Feb 2006]
Uniprot Description
Function: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E
By similarity.
Subunit structure: Monomer
By similarity. Interacts with phosphorylated CLDN7. Ref.4
Subcellular location: Lateral cell membrane; Single-pass type I membrane protein. Cell junction › tight junction. Note: Co-localizes with CLDN7 at the lateral cell membrane and tight junction. Ref.4
Post-translational modification: Glycosylation at Asn-198 is crucial for protein stability
By similarity.
Sequence similarities: Belongs to the EPCAM family.Contains 1 thyroglobulin type-1 domain.
Research Articles on Epcam
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Product Notes
The Epcam epcam (Catalog #AAA313070) is an Antibody produced from Host: Mouse. Hybridization of Sp2/0 myeloma cells with spleen cells from BALB/c mice.; Source: Ascites and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Epithelial Cell Adhesion Molecule (Ep CAM) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the Epcam epcam for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Epithelial Cell Adhesion Molecule (Ep CAM), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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