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Western Blot (WB) (Western blot analysis of extracts from HepG2 cells, using AZI2 antibody.)

AZI2 Antibody | anti-AZI2 antibody

AZI2 Antibody

Gene Names
AZI2; AZ2; NAP1; TILP
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
AZI2; AZI2 Antibody; 5-azacytidine-induced protein 2; NF-kappa-B-activating kinase-associated protein 1; Nak-associated protein 1; TILP; NAP1; anti-AZI2 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
AZI2 antibody detects endogenous levels of total AZI2 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
243
Applicable Applications for anti-AZI2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from N-terminal of human AZI2.
Preparation and Storage
Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from HepG2 cells, using AZI2 antibody.)

Western Blot (WB) (Western blot analysis of extracts from HepG2 cells, using AZI2 antibody.)
References
Fujita F., Mol. Cell. Biol. 23:7780-7793(2003). Ota T., Nat. Genet. 36:40-45(2004). Sasai M., J. Immunol. 174:27-30(2005).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,921 Da
NCBI Official Full Name
5-azacytidine-induced protein 2 isoform b
NCBI Official Synonym Full Names
5-azacytidine induced 2
NCBI Official Symbol
AZI2
NCBI Official Synonym Symbols
AZ2; NAP1; TILP
NCBI Protein Information
5-azacytidine-induced protein 2
UniProt Protein Name
5-azacytidine-induced protein 2
UniProt Gene Name
AZI2
UniProt Synonym Gene Names
NAP1; TBKBP2; Nak-associated protein 1

NCBI Description

AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003 [PubMed 14560022]).[supplied by OMIM, Mar 2008]

Uniprot Description

Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.

Research Articles on AZI2

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Product Notes

The AZI2 azi2 (Catalog #AAA858350) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The AZI2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's AZI2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:20000. Researchers should empirically determine the suitability of the AZI2 azi2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AZI2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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